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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM181B
All Species:
17.27
Human Site:
Y395
Identified Species:
54.29
UniProt:
A6NEQ2
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NEQ2
NP_787081.2
426
42657
Y395
P
H
Q
V
S
Y
D
Y
S
A
G
Y
S
R
T
Chimpanzee
Pan troglodytes
XP_001175137
426
42677
Y395
P
H
Q
V
S
Y
D
Y
S
A
G
Y
S
R
T
Rhesus Macaque
Macaca mulatta
XP_001095747
426
42685
Y395
P
H
Q
V
S
Y
D
Y
S
A
G
Y
S
R
N
Dog
Lupus familis
XP_850835
257
26672
G235
S
G
V
F
S
E
G
G
S
R
S
A
P
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80VF6
417
42418
Y386
P
H
Q
V
S
Y
D
Y
S
A
G
Y
S
R
A
Rat
Rattus norvegicus
NP_001102620
419
42855
Y388
P
H
Q
V
S
Y
D
Y
S
A
G
Y
S
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235466
320
32791
P298
G
P
F
F
P
E
C
P
L
P
P
P
Q
M
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001336095
321
35262
D299
T
F
S
N
F
L
T
D
C
S
T
P
P
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.7
39.9
N.A.
77.2
76.7
N.A.
N.A.
45.7
N.A.
36.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
96.4
46.2
N.A.
82.3
81.9
N.A.
N.A.
52.3
N.A.
47.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
63
0
13
0
13
25
% A
% Cys:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
63
13
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
13
13
25
13
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
13
0
0
0
0
13
13
0
0
63
0
0
13
0
% G
% His:
0
63
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
13
0
0
13
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
13
% N
% Pro:
63
13
0
0
13
0
0
13
0
13
13
25
25
0
13
% P
% Gln:
0
0
63
0
0
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
0
0
0
63
13
% R
% Ser:
13
0
13
0
75
0
0
0
75
13
13
0
63
0
13
% S
% Thr:
13
0
0
0
0
0
13
0
0
0
13
0
0
0
25
% T
% Val:
0
0
13
63
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
63
0
63
0
0
0
63
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _