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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D3E
All Species:
8.18
Human Site:
S543
Identified Species:
25.71
UniProt:
A6NER0
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NER0
NP_001035372
549
62199
S543
C
G
L
H
L
E
S
S
Q
F
P
P
G
F
_
Chimpanzee
Pan troglodytes
XP_001173074
549
62288
S543
C
G
L
H
L
E
S
S
R
F
P
P
G
F
_
Rhesus Macaque
Macaca mulatta
XP_001112605
584
64806
N574
A
T
S
S
A
A
L
N
L
Y
G
F
G
S
S
Dog
Lupus familis
XP_544260
839
96074
S802
S
P
V
R
Y
R
T
S
P
G
L
E
D
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80XC3
819
93555
S582
P
R
K
H
P
E
P
S
P
S
P
P
K
V
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508840
842
96631
S690
S
N
L
S
V
D
F
S
P
E
K
S
Y
N
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GLZ0
342
39660
Zebra Danio
Brachydanio rerio
Q6PBU5
356
41604
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
55.9
23.9
N.A.
24.6
N.A.
N.A.
24.9
N.A.
20.7
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.1
63.3
37.9
N.A.
37.9
N.A.
N.A.
38.5
N.A.
34.9
33.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
92.8
6.6
6.6
N.A.
33.3
N.A.
N.A.
13.3
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
33.3
N.A.
N.A.
26.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
13
13
0
0
0
0
0
0
0
13
0
% A
% Cys:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
0
0
0
0
0
0
13
0
0
% D
% Glu:
0
0
0
0
0
38
0
0
0
13
0
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
13
0
0
25
0
13
0
25
0
% F
% Gly:
0
25
0
0
0
0
0
0
0
13
13
0
38
0
0
% G
% His:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
13
0
13
0
0
% K
% Leu:
0
0
38
0
25
0
13
0
13
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
13
0
0
0
0
0
13
0
% N
% Pro:
13
13
0
0
13
0
13
0
38
0
38
38
0
0
13
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
13
0
13
0
13
0
0
13
0
0
0
0
0
13
% R
% Ser:
25
0
13
25
0
0
25
63
0
13
0
13
0
13
25
% S
% Thr:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% T
% Val:
0
0
13
0
13
0
0
0
0
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
13
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% _