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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 21.52
Human Site: Y60 Identified Species: 47.33
UniProt: A6NEY8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NEY8 NULL 169 18658 Y60 K D K K K K N Y W L V T V L H
Chimpanzee Pan troglodytes XP_525758 320 35753 Y209 K D K K K K N Y W L V T V L H
Rhesus Macaque Macaca mulatta XP_001112311 247 27057 Y135 K D K K K K N Y W L V T V L H
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9D820 169 18843 Y60 K D K K K K N Y W L V T V L H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510211 174 19436 F62 K D K K K K G F W L V T V L H
Chicken Gallus gallus XP_419287 309 33938 F196 K D K K R K E F W L V T V L H
Frog Xenopus laevis Q6NRL0 168 18909 L59 K D K K K K G L W L V S V L H
Zebra Danio Brachydanio rerio Q6PFS2 184 20696 F77 K D K K R R V F L V C V R H D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779908 181 19759 Y71 K D K K K R L Y L L T A L H D
Poplar Tree Populus trichocarpa XP_002307426 287 31048 Y58 K D K K S R F Y I V S A L A D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001031149 308 33791 Y58 K D K K H R Y Y I V S A M V D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51.5 67.2 N.A. N.A. 93.4 N.A. N.A. 76.4 44.6 73.9 51.6 N.A. N.A. N.A. N.A. 52.4
Protein Similarity: 100 52.1 67.2 N.A. N.A. 95.8 N.A. N.A. 85 49.8 86.3 64.6 N.A. N.A. N.A. N.A. 65.7
P-Site Identity: 100 100 100 N.A. N.A. 100 N.A. N.A. 86.6 80 80 26.6 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 N.A. N.A. 93.3 93.3 86.6 53.3 N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: 23.6 N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: 36.9 N.A. N.A. 33.7 N.A. N.A.
P-Site Identity: 33.3 N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: 53.3 N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 28 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 37 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 28 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 19 64 % H
% Ile: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % I
% Lys: 100 0 100 100 64 64 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 10 19 73 0 0 19 64 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 37 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 19 37 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 10 0 0 0 0 0 19 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 55 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 28 64 10 64 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 64 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _