KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB10
All Species:
10.3
Human Site:
S77
Identified Species:
25.19
UniProt:
A6NFE3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NFE3
NULL
127
14721
S77
A
M
F
E
M
M
D
S
S
G
R
G
T
I
S
Chimpanzee
Pan troglodytes
XP_519297
131
15208
S77
A
M
F
E
M
M
D
S
S
G
R
G
T
I
S
Rhesus Macaque
Macaca mulatta
XP_001087039
126
14531
K84
T
I
S
F
V
Q
Y
K
E
A
L
K
T
L
G
Dog
Lupus familis
XP_852189
132
15348
T78
A
M
F
E
M
M
D
T
S
S
K
G
T
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D581
132
15544
M78
S
M
F
E
M
M
D
M
A
G
R
G
C
I
S
Rat
Rattus norvegicus
NP_001102176
132
15383
N78
S
M
F
E
M
M
D
N
A
G
K
G
T
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508707
121
13735
P79
S
M
F
E
M
M
D
P
S
K
Q
G
Y
I
T
Chicken
Gallus gallus
XP_001232475
127
14175
V81
D
A
A
G
R
G
F
V
T
G
R
Q
C
R
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SX95
200
23000
S87
L
K
Q
Q
V
P
L
S
S
D
S
S
R
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792934
135
15530
K79
G
M
L
D
P
T
K
K
G
H
I
T
L
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
72.4
75
N.A.
68.9
71.9
N.A.
50.3
39.3
N.A.
20.5
N.A.
N.A.
N.A.
N.A.
34.8
Protein Similarity:
100
96.9
79.5
86.3
N.A.
81
85.6
N.A.
77.1
64.5
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
58.5
P-Site Identity:
100
100
6.6
80
N.A.
73.3
73.3
N.A.
60
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
93.3
N.A.
86.6
100
N.A.
80
26.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
10
10
0
0
0
0
0
20
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% C
% Asp:
10
0
0
10
0
0
60
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
60
0
0
0
0
10
0
0
0
0
10
0
% E
% Phe:
0
0
60
10
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
10
0
0
10
50
0
60
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
10
0
0
60
0
% I
% Lys:
0
10
0
0
0
0
10
20
0
10
20
10
0
0
0
% K
% Leu:
10
0
10
0
0
0
10
0
0
0
10
0
10
10
0
% L
% Met:
0
70
0
0
60
60
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
10
0
0
0
0
10
10
0
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
40
0
10
10
0
% R
% Ser:
30
0
10
0
0
0
0
30
50
10
10
10
0
0
50
% S
% Thr:
10
0
0
0
0
10
0
10
10
0
0
10
50
0
20
% T
% Val:
0
0
0
0
20
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _