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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFCAB10 All Species: 19.09
Human Site: Y13 Identified Species: 46.67
UniProt: A6NFE3 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NFE3 NULL 127 14721 Y13 R E L Q A A E Y L E K H Q I K
Chimpanzee Pan troglodytes XP_519297 131 15208 Y13 R E L Q A A E Y L E K H Q I K
Rhesus Macaque Macaca mulatta XP_001087039 126 14531 R20 F S K S L P R R L Q C L C W V
Dog Lupus familis XP_852189 132 15348 Y14 R E L E A R N Y L E K H R I M
Cat Felis silvestris
Mouse Mus musculus Q9D581 132 15544 Y14 R E L Q A K L Y L E R H R I M
Rat Rattus norvegicus NP_001102176 132 15383 Y14 R E L Q A K L Y L E K H R I M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508707 121 13735 Y15 E E A A A Q A Y L S Q H R I P
Chicken Gallus gallus XP_001232475 127 14175 L17 E Y L E R H G L P A L L H R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SX95 200 23000 R23 E Y L E R R E R E A E H G Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792934 135 15530 T15 E T N E Y L D T H R I P E L F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 72.4 75 N.A. 68.9 71.9 N.A. 50.3 39.3 N.A. 20.5 N.A. N.A. N.A. N.A. 34.8
Protein Similarity: 100 96.9 79.5 86.3 N.A. 81 85.6 N.A. 77.1 64.5 N.A. 35.5 N.A. N.A. N.A. N.A. 58.5
P-Site Identity: 100 100 6.6 66.6 N.A. 66.6 73.3 N.A. 40 6.6 N.A. 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 13.3 80 N.A. 80 80 N.A. 53.3 13.3 N.A. 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 60 20 10 0 0 20 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 40 60 0 40 0 0 30 0 10 50 10 0 10 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 10 0 0 10 0 0 70 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 60 0 % I
% Lys: 0 0 10 0 0 20 0 0 0 0 40 0 0 0 20 % K
% Leu: 0 0 70 0 10 10 20 10 70 0 10 20 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 % M
% Asn: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 10 0 0 10 0 0 10 % P
% Gln: 0 0 0 40 0 10 0 0 0 10 10 0 20 0 0 % Q
% Arg: 50 0 0 0 20 20 10 20 0 10 10 0 40 10 0 % R
% Ser: 0 10 0 10 0 0 0 0 0 10 0 0 0 0 0 % S
% Thr: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 20 0 0 10 0 0 60 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _