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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB10
All Species:
19.7
Human Site:
Y41
Identified Species:
48.15
UniProt:
A6NFE3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NFE3
NULL
127
14721
Y41
R
P
E
K
P
K
E
Y
L
I
S
L
L
E
R
Chimpanzee
Pan troglodytes
XP_519297
131
15208
Y41
R
P
E
K
P
K
E
Y
L
I
S
L
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001087039
126
14531
K48
L
E
R
L
R
I
A
K
V
T
G
V
A
F
P
Dog
Lupus familis
XP_852189
132
15348
Y42
R
P
E
K
P
R
E
Y
L
I
T
I
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D581
132
15544
Y42
R
P
K
K
P
R
E
Y
L
I
S
L
L
E
R
Rat
Rattus norvegicus
NP_001102176
132
15383
Y42
R
P
K
K
P
R
D
Y
L
I
S
L
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508707
121
13735
F43
R
P
E
R
L
R
E
F
L
I
S
L
L
E
R
Chicken
Gallus gallus
XP_001232475
127
14175
E45
Q
F
L
I
Q
V
L
E
A
V
R
A
A
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SX95
200
23000
S51
R
K
K
Q
K
S
K
S
H
S
S
P
G
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792934
135
15530
D43
N
P
K
T
F
M
I
D
Y
I
S
K
L
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
72.4
75
N.A.
68.9
71.9
N.A.
50.3
39.3
N.A.
20.5
N.A.
N.A.
N.A.
N.A.
34.8
Protein Similarity:
100
96.9
79.5
86.3
N.A.
81
85.6
N.A.
77.1
64.5
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
58.5
P-Site Identity:
100
100
0
80
N.A.
86.6
80
N.A.
73.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
93.3
20
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
10
0
0
10
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% D
% Glu:
0
10
40
0
0
0
50
10
0
0
0
0
0
60
10
% E
% Phe:
0
10
0
0
10
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
10
0
0
70
0
10
0
0
0
% I
% Lys:
0
10
40
50
10
20
10
10
0
0
0
10
0
10
0
% K
% Leu:
10
0
10
10
10
0
10
0
60
0
0
50
70
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
70
0
0
50
0
0
0
0
0
0
10
0
0
10
% P
% Gln:
10
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
70
0
10
10
10
40
0
0
0
0
10
0
0
10
70
% R
% Ser:
0
0
0
0
0
10
0
10
0
10
70
0
0
0
10
% S
% Thr:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
10
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _