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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 6.36
Human Site: T188 Identified Species: 15.56
UniProt: A6NFU8 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NFU8 NP_001096082.1 196 21675 T188 A Q F E E N S T M V L P A K G
Chimpanzee Pan troglodytes XP_523167 196 21554 T188 A Q F K E N S T M V L P A K G
Rhesus Macaque Macaca mulatta XP_001108144 643 69012 T632 R K L N H G A T S Q R E L T G
Dog Lupus familis XP_545829 190 20160 A182 P E L K A W F A E N S T S E P
Cat Felis silvestris
Mouse Mus musculus Q9CWB5 130 14249 K122 E M L E E I G K V Q T Q S T A
Rat Rattus norvegicus Q76IC5 209 22895 D202 V L E Q A E G D I S C C H Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425083 148 16577 K141 T I I L E M L K Q C W E Q R E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018362 208 23080 T197 E M L E H M E T Q Q T N T H C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_492491 208 23185 V193 E E C T K E A V T E V I R E T
Sea Urchin Strong. purpuratus XP_786904 206 22870 I199 L L F M L Q Q I D E R T A K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.4 25.5 52 N.A. 45.9 39.2 N.A. N.A. 40.8 N.A. 42.7 N.A. N.A. N.A. 22.1 33.9
Protein Similarity: 100 98.4 26.9 64.2 N.A. 53 56.4 N.A. N.A. 55.6 N.A. 55.2 N.A. N.A. N.A. 37.5 50
P-Site Identity: 100 93.3 13.3 0 N.A. 13.3 0 N.A. N.A. 6.6 N.A. 13.3 N.A. N.A. N.A. 0 20
P-Site Similarity: 100 100 26.6 26.6 N.A. 26.6 20 N.A. N.A. 13.3 N.A. 13.3 N.A. N.A. N.A. 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 20 0 20 10 0 0 0 0 30 0 10 % A
% Cys: 0 0 10 0 0 0 0 0 0 10 10 10 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % D
% Glu: 30 20 10 30 40 20 10 0 10 20 0 20 0 20 10 % E
% Phe: 0 0 30 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 20 0 0 0 0 0 0 0 30 % G
% His: 0 0 0 0 20 0 0 0 0 0 0 0 10 10 0 % H
% Ile: 0 10 10 0 0 10 0 10 10 0 0 10 0 0 0 % I
% Lys: 0 10 0 20 10 0 0 20 0 0 0 0 0 30 0 % K
% Leu: 10 20 40 10 10 0 10 0 0 0 20 0 10 0 10 % L
% Met: 0 20 0 10 0 20 0 0 20 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 20 0 0 0 10 0 10 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 20 0 0 10 % P
% Gln: 0 20 0 10 0 10 10 0 20 30 0 10 10 10 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 20 0 10 10 0 % R
% Ser: 0 0 0 0 0 0 20 0 10 10 10 0 20 0 10 % S
% Thr: 10 0 0 10 0 0 0 40 10 0 20 20 10 20 10 % T
% Val: 10 0 0 0 0 0 0 10 10 20 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _