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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 26.97
Human Site: Y125 Identified Species: 65.93
UniProt: A6NFU8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NFU8 NP_001096082.1 196 21675 Y125 F S R D A G R Y V C D Y T Y Y
Chimpanzee Pan troglodytes XP_523167 196 21554 Y125 F S R D A G R Y V C D Y T Y Y
Rhesus Macaque Macaca mulatta XP_001108144 643 69012 Y565 F S R D A G R Y V C D Y T Y Y
Dog Lupus familis XP_545829 190 20160 Y123 V S G D A G R Y V C E Y T Y Y
Cat Felis silvestris
Mouse Mus musculus Q9CWB5 130 14249 Y75 A G R Y I C D Y T Y Y L S L P
Rat Rattus norvegicus Q76IC5 209 22895 Y147 I S Q D A G R Y L C D F T Y Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425083 148 16577 I95 S R D A G R Y I C D Y T Y Y T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018362 208 23080 Y146 V S K D A G R Y L C D Y T Y Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_492491 208 23185 Y145 C A L D G Q K Y S G L C V K K
Sea Urchin Strong. purpuratus XP_786904 206 22870 Y150 V S Y N A G R Y L C G Y C Y Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.4 25.5 52 N.A. 45.9 39.2 N.A. N.A. 40.8 N.A. 42.7 N.A. N.A. N.A. 22.1 33.9
Protein Similarity: 100 98.4 26.9 64.2 N.A. 53 56.4 N.A. N.A. 55.6 N.A. 55.2 N.A. N.A. N.A. 37.5 50
P-Site Identity: 100 100 100 80 N.A. 13.3 73.3 N.A. N.A. 6.6 N.A. 80 N.A. N.A. N.A. 13.3 60
P-Site Similarity: 100 100 100 86.6 N.A. 20 93.3 N.A. N.A. 6.6 N.A. 93.3 N.A. N.A. N.A. 26.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 70 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 10 0 0 0 0 10 0 0 10 70 0 10 10 0 0 % C
% Asp: 0 0 10 70 0 0 10 0 0 10 50 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 30 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 10 10 0 20 70 0 0 0 10 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 10 0 0 0 0 0 0 10 10 % K
% Leu: 0 0 10 0 0 0 0 0 30 0 10 10 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 40 0 0 10 70 0 0 0 0 0 0 0 0 % R
% Ser: 10 70 0 0 0 0 0 0 10 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 10 60 0 10 % T
% Val: 30 0 0 0 0 0 0 0 40 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 0 10 90 0 10 20 60 10 80 70 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _