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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHAF1
All Species:
18.18
Human Site:
S45
Identified Species:
44.44
UniProt:
A6NFY7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NFY7
NP_001036096.1
115
12806
S45
Q
H
A
G
L
P
R
S
D
V
L
R
I
E
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100760
115
12814
S45
Q
H
A
G
L
P
R
S
D
V
L
R
I
E
Y
Dog
Lupus familis
XP_541681
118
12884
S45
Q
H
A
S
L
P
R
S
D
V
L
R
I
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3U276
118
13123
T45
Q
H
A
S
L
P
R
T
D
V
L
R
I
E
Y
Rat
Rattus norvegicus
B0K036
118
13294
S45
Q
H
A
S
L
P
R
S
D
V
L
R
I
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518072
82
9646
S13
K
L
Q
R
Q
V
L
S
L
Y
R
Q
F
L
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RIM0
88
10472
R19
S
L
K
Q
F
L
Q
R
Q
K
V
L
C
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182916
103
11829
I32
K
P
G
V
K
P
Q
I
K
Y
E
F
R
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147276
88
10274
R19
K
Q
V
L
A
L
Y
R
G
F
L
R
T
A
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565912
90
10355
L21
L
S
L
Y
R
G
F
L
R
A
A
R
S
R
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
81.3
N.A.
77.9
79.6
N.A.
52.1
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
38.2
Protein Similarity:
100
N.A.
97.3
84.7
N.A.
83
83.9
N.A.
60
N.A.
N.A.
34.7
N.A.
N.A.
N.A.
N.A.
56.5
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
93.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
20
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
27.8
N.A.
23.4
N.A.
N.A.
Protein Similarity:
N.A.
40
N.A.
37.3
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
10
0
0
0
0
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
50
0
% E
% Phe:
0
0
0
0
10
0
10
0
0
10
0
10
10
0
0
% F
% Gly:
0
0
10
20
0
10
0
0
10
0
0
0
0
0
10
% G
% His:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
50
0
0
% I
% Lys:
30
0
10
0
10
0
0
0
10
10
0
0
0
10
0
% K
% Leu:
10
20
10
10
50
20
10
10
10
0
60
10
0
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
60
0
0
0
0
0
0
0
0
10
% P
% Gln:
50
10
10
10
10
0
20
0
10
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
10
0
50
20
10
0
10
70
10
10
20
% R
% Ser:
10
10
0
30
0
0
0
50
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% T
% Val:
0
0
10
10
0
10
0
0
0
50
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
0
20
0
0
0
0
60
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _