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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDHAF1 All Species: 18.48
Human Site: S66 Identified Species: 45.19
UniProt: A6NFY7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NFY7 NP_001036096.1 115 12806 S66 R Q L Q L L R S G H A T A M G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100760 115 12814 S66 R Q L Q L L R S G H A T A M G
Dog Lupus familis XP_541681 118 12884 S66 R Q L Q L L R S G H A K A M G
Cat Felis silvestris
Mouse Mus musculus Q3U276 118 13123 S66 R Q L Q L L R S G H A T A M G
Rat Rattus norvegicus B0K036 118 13294 S66 R Q L Q L L R S G H A T A M G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518072 82 9646 A34 G A V S R I R A E F R Q H A R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5RIM0 88 10472 S40 I R R V P H E S D R K Y L R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182916 103 11829 V53 D L M R I E Y V M R R A E R Q
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001147276 88 10274 V40 R R R I E S V V F A E F R D N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565912 90 10355 E42 I E M I V S T E F R H N S K E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.3 81.3 N.A. 77.9 79.6 N.A. 52.1 N.A. N.A. 20 N.A. N.A. N.A. N.A. 38.2
Protein Similarity: 100 N.A. 97.3 84.7 N.A. 83 83.9 N.A. 60 N.A. N.A. 34.7 N.A. N.A. N.A. N.A. 56.5
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 6.6 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 26.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 27.8 N.A. 23.4 N.A. N.A.
Protein Similarity: N.A. 40 N.A. 37.3 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 10 0 10 50 10 50 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 10 0 0 0 0 10 10 % D
% Glu: 0 10 0 0 10 10 10 10 10 0 10 0 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 20 10 0 10 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 50 0 0 0 0 0 50 % G
% His: 0 0 0 0 0 10 0 0 0 50 10 0 10 0 0 % H
% Ile: 20 0 0 20 10 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 10 0 10 0 % K
% Leu: 0 10 50 0 50 50 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 20 0 0 0 0 0 10 0 0 0 0 50 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 50 0 50 0 0 0 0 0 0 0 10 0 0 10 % Q
% Arg: 60 20 20 10 10 0 60 0 0 30 20 0 10 20 10 % R
% Ser: 0 0 0 10 0 20 0 60 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 40 0 0 0 % T
% Val: 0 0 10 10 10 0 10 20 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _