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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WIPF3
All Species:
18.79
Human Site:
T453
Identified Species:
51.67
UniProt:
A6NGB9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NGB9
NP_001073998.1
483
49348
T453
S
K
I
P
R
S
R
T
P
G
P
W
L
Q
A
Chimpanzee
Pan troglodytes
XP_001164871
483
49711
T453
S
K
I
P
R
S
R
T
P
G
P
W
L
Q
A
Rhesus Macaque
Macaca mulatta
XP_001087108
486
49833
T456
S
K
I
P
R
S
R
T
P
G
P
W
L
Q
A
Dog
Lupus familis
XP_850217
440
46420
S398
S
F
L
D
D
F
E
S
K
Y
S
F
H
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P0C7L0
485
49434
T453
S
K
V
P
R
S
R
T
P
G
S
W
L
Q
A
Rat
Rattus norvegicus
Q9Z0G8
485
49362
T455
S
K
V
P
R
S
R
T
P
G
S
W
L
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418733
254
27578
R225
L
L
P
L
C
P
L
R
Q
K
D
L
P
R
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665566
492
51905
P456
E
S
K
F
H
F
H
P
I
E
D
F
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37370
817
82575
G769
S
I
V
G
A
K
S
G
N
E
R
I
V
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
96
35.2
N.A.
78.3
78.9
N.A.
N.A.
28.3
N.A.
40.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95
96.9
43.4
N.A.
82.6
83.7
N.A.
N.A.
33.5
N.A.
52
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
86.6
86.6
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
93.3
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
56
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
12
0
0
0
0
0
23
0
0
0
12
% D
% Glu:
12
0
0
0
0
0
12
0
0
23
0
0
0
0
12
% E
% Phe:
0
12
0
12
0
23
0
0
0
0
0
23
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
12
0
56
0
0
0
0
0
% G
% His:
0
0
0
0
12
0
12
0
0
0
0
0
12
0
0
% H
% Ile:
0
12
34
0
0
0
0
0
12
0
0
12
0
12
0
% I
% Lys:
0
56
12
0
0
12
0
0
12
12
0
0
0
0
0
% K
% Leu:
12
12
12
12
0
0
12
0
0
0
0
12
56
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
12
56
0
12
0
12
56
0
34
0
23
23
12
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
0
0
56
0
% Q
% Arg:
0
0
0
0
56
0
56
12
0
0
12
0
0
12
0
% R
% Ser:
78
12
0
0
0
56
12
12
0
0
34
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% T
% Val:
0
0
34
0
0
0
0
0
0
0
0
0
12
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
56
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _