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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLCD2
All Species:
18.79
Human Site:
S229
Identified Species:
41.33
UniProt:
A6NGC4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NGC4
NP_001157879.1
264
28733
S229
L
V
N
D
V
L
Q
S
R
P
H
P
P
S
P
Chimpanzee
Pan troglodytes
XP_001174204
437
46242
S402
L
V
N
D
V
L
Q
S
R
P
H
P
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001117332
467
50594
S432
L
V
N
D
V
L
R
S
R
P
H
P
P
S
P
Dog
Lupus familis
XP_853993
264
28572
S229
L
V
S
D
V
L
R
S
R
P
H
S
P
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC26
310
34121
S228
L
T
K
D
I
L
Q
S
Q
P
Y
P
F
I
L
Rat
Rattus norvegicus
Q5U2T1
247
28711
M213
F
L
L
S
I
L
L
M
L
D
V
M
I
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425399
241
27327
V207
A
T
Y
T
V
G
T
V
G
M
A
I
M
T
P
Frog
Xenopus laevis
Q6GLX2
258
29536
V224
A
W
I
V
S
C
V
V
L
D
I
L
N
V
F
Zebra Danio
Brachydanio rerio
A8WGS4
246
28315
T212
S
V
G
L
A
I
M
T
A
M
N
I
V
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493466
350
39805
G298
L
A
A
D
G
L
L
G
S
R
R
T
R
R
T
Sea Urchin
Strong. purpuratus
XP_789953
151
17363
T117
L
L
A
G
V
G
L
T
V
M
L
S
V
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.2
53.3
77.6
N.A.
62.2
27.6
N.A.
N.A.
43.5
25.3
34.4
N.A.
N.A.
N.A.
26
23.4
Protein Similarity:
100
56.9
54.5
85.2
N.A.
68.3
46.5
N.A.
N.A.
59
42.4
57.9
N.A.
N.A.
N.A.
40.5
38.6
P-Site Identity:
100
100
93.3
73.3
N.A.
46.6
6.6
N.A.
N.A.
13.3
0
6.6
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
20
N.A.
N.A.
20
0
26.6
N.A.
N.A.
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
19
0
10
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
55
0
0
0
0
0
19
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
28
% F
% Gly:
0
0
10
10
10
19
0
10
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% H
% Ile:
0
0
10
0
19
10
0
0
0
0
10
19
10
19
10
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
64
19
10
10
0
64
28
0
19
0
10
10
0
19
10
% L
% Met:
0
0
0
0
0
0
10
10
0
28
0
10
10
0
0
% M
% Asn:
0
0
28
0
0
0
0
0
0
0
10
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
46
0
37
37
0
46
% P
% Gln:
0
0
0
0
0
0
28
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
19
0
37
10
10
0
10
10
0
% R
% Ser:
10
0
10
10
10
0
0
46
10
0
0
19
0
28
0
% S
% Thr:
0
19
0
10
0
0
10
19
0
0
0
10
0
10
10
% T
% Val:
0
46
0
10
55
0
10
19
10
0
10
0
19
10
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _