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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLCD2
All Species:
3.03
Human Site:
S255
Identified Species:
6.67
UniProt:
A6NGC4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NGC4
NP_001157879.1
264
28733
S255
R
D
N
G
P
V
T
S
N
S
S
T
L
S
L
Chimpanzee
Pan troglodytes
XP_001174204
437
46242
R428
R
D
N
G
P
V
T
R
N
S
S
T
L
S
L
Rhesus Macaque
Macaca mulatta
XP_001117332
467
50594
R458
R
D
D
G
P
V
T
R
D
N
S
T
L
S
L
Dog
Lupus familis
XP_853993
264
28572
R255
C
D
G
E
L
V
T
R
E
D
S
T
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC26
310
34121
S254
A
R
N
T
S
T
L
S
L
K
G
S
R
Y
L
Rat
Rattus norvegicus
Q5U2T1
247
28711
Q239
P
E
R
A
P
S
R
Q
Q
K
D
K
F
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425399
241
27327
R233
S
D
F
F
K
S
S
R
D
T
R
R
E
K
E
Frog
Xenopus laevis
Q6GLX2
258
29536
G250
V
V
K
A
K
P
D
G
K
P
R
R
N
H
A
Zebra Danio
Brachydanio rerio
A8WGS4
246
28315
K238
S
R
E
K
E
L
R
K
E
K
E
K
E
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493466
350
39805
T324
V
E
S
G
P
L
R
T
Q
V
E
D
E
D
H
Sea Urchin
Strong. purpuratus
XP_789953
151
17363
E143
L
S
R
R
N
C
K
E
S
K
D
D
V
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.2
53.3
77.6
N.A.
62.2
27.6
N.A.
N.A.
43.5
25.3
34.4
N.A.
N.A.
N.A.
26
23.4
Protein Similarity:
100
56.9
54.5
85.2
N.A.
68.3
46.5
N.A.
N.A.
59
42.4
57.9
N.A.
N.A.
N.A.
40.5
38.6
P-Site Identity:
100
93.3
73.3
53.3
N.A.
20
6.6
N.A.
N.A.
6.6
0
0
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
93.3
93.3
53.3
N.A.
26.6
13.3
N.A.
N.A.
26.6
0
6.6
N.A.
N.A.
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
19
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
10
0
0
0
10
0
19
10
19
19
0
10
19
% D
% Glu:
0
19
10
10
10
0
0
10
19
0
19
0
28
0
10
% E
% Phe:
0
0
10
10
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
10
37
0
0
0
10
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
19
0
10
10
10
37
0
19
0
19
0
% K
% Leu:
10
0
0
0
10
19
10
0
10
0
0
0
37
10
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
28
0
10
0
0
0
19
10
0
0
10
0
0
% N
% Pro:
10
0
0
0
46
10
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
19
0
0
0
0
0
0
% Q
% Arg:
28
19
19
10
0
0
28
37
0
0
19
19
10
0
0
% R
% Ser:
19
10
10
0
10
19
10
19
10
19
37
10
0
37
0
% S
% Thr:
0
0
0
10
0
10
37
10
0
10
0
37
0
0
10
% T
% Val:
19
10
0
0
0
37
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _