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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLCD2
All Species:
12.48
Human Site:
S261
Identified Species:
27.45
UniProt:
A6NGC4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NGC4
NP_001157879.1
264
28733
S261
T
S
N
S
S
T
L
S
L
K
D
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001174204
437
46242
S434
T
R
N
S
S
T
L
S
L
K
D
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001117332
467
50594
S464
T
R
D
N
S
T
L
S
L
K
D
_
_
_
_
Dog
Lupus familis
XP_853993
264
28572
S261
T
R
E
D
S
T
L
S
L
Q
D
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC26
310
34121
Y260
L
S
L
K
G
S
R
Y
L
Y
S
T
A
A
A
Rat
Rattus norvegicus
Q5U2T1
247
28711
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425399
241
27327
Frog
Xenopus laevis
Q6GLX2
258
29536
Zebra Danio
Brachydanio rerio
A8WGS4
246
28315
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493466
350
39805
D330
R
T
Q
V
E
D
E
D
H
H
T
I
G
V
Q
Sea Urchin
Strong. purpuratus
XP_789953
151
17363
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.2
53.3
77.6
N.A.
62.2
27.6
N.A.
N.A.
43.5
25.3
34.4
N.A.
N.A.
N.A.
26
23.4
Protein Similarity:
100
56.9
54.5
85.2
N.A.
68.3
46.5
N.A.
N.A.
59
42.4
57.9
N.A.
N.A.
N.A.
40.5
38.6
P-Site Identity:
100
90.9
72.7
63.6
N.A.
13.3
0
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
90.9
90.9
72.7
N.A.
20
0
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
10
0
10
0
0
37
0
0
0
0
% D
% Glu:
0
0
10
0
10
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
28
0
0
0
0
0
% K
% Leu:
10
0
10
0
0
0
37
0
46
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
19
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
10
28
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
19
0
19
37
10
0
37
0
0
10
0
0
0
0
% S
% Thr:
37
10
0
0
0
37
0
0
0
0
10
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
37
37
37
37
% _