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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLCD2
All Species:
12.73
Human Site:
T244
Identified Species:
28
UniProt:
A6NGC4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NGC4
NP_001157879.1
264
28733
T244
G
H
E
K
T
R
G
T
R
T
R
R
D
N
G
Chimpanzee
Pan troglodytes
XP_001174204
437
46242
T417
G
R
E
K
T
R
G
T
R
T
R
R
D
N
G
Rhesus Macaque
Macaca mulatta
XP_001117332
467
50594
T447
G
H
E
K
T
R
G
T
R
T
H
R
D
D
G
Dog
Lupus familis
XP_853993
264
28572
T244
G
H
K
E
T
R
G
T
R
G
C
C
D
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC26
310
34121
R243
M
H
K
E
T
K
T
R
E
P
V
A
R
N
T
Rat
Rattus norvegicus
Q5U2T1
247
28711
S228
Y
F
S
R
L
L
R
S
D
F
C
P
E
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425399
241
27327
R222
M
N
I
I
L
F
Y
R
L
L
R
S
D
F
F
Frog
Xenopus laevis
Q6GLX2
258
29536
G239
W
M
Y
K
I
A
R
G
F
Y
K
V
V
K
A
Zebra Danio
Brachydanio rerio
A8WGS4
246
28315
F227
Y
R
L
M
R
S
D
F
M
K
A
S
R
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493466
350
39805
Q313
P
A
A
T
A
E
T
Q
V
G
D
V
E
S
G
Sea Urchin
Strong. purpuratus
XP_789953
151
17363
S132
V
L
F
L
R
L
L
S
S
D
F
L
S
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.2
53.3
77.6
N.A.
62.2
27.6
N.A.
N.A.
43.5
25.3
34.4
N.A.
N.A.
N.A.
26
23.4
Protein Similarity:
100
56.9
54.5
85.2
N.A.
68.3
46.5
N.A.
N.A.
59
42.4
57.9
N.A.
N.A.
N.A.
40.5
38.6
P-Site Identity:
100
93.3
86.6
53.3
N.A.
20
0
N.A.
N.A.
13.3
6.6
0
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
93.3
93.3
66.6
N.A.
40
20
N.A.
N.A.
20
13.3
0
N.A.
N.A.
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
10
0
0
0
0
10
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
19
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
10
10
0
46
10
0
% D
% Glu:
0
0
28
19
0
10
0
0
10
0
0
0
19
10
10
% E
% Phe:
0
10
10
0
0
10
0
10
10
10
10
0
0
10
10
% F
% Gly:
37
0
0
0
0
0
37
10
0
19
0
0
0
10
37
% G
% His:
0
37
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
19
37
0
10
0
0
0
10
10
0
0
10
10
% K
% Leu:
0
10
10
10
19
19
10
0
10
10
0
10
0
0
0
% L
% Met:
19
10
0
10
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
28
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
19
0
10
19
37
19
19
37
0
28
28
19
19
10
% R
% Ser:
0
0
10
0
0
10
0
19
10
0
0
19
10
10
0
% S
% Thr:
0
0
0
10
46
0
19
37
0
28
0
0
0
0
10
% T
% Val:
10
0
0
0
0
0
0
0
10
0
10
19
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
0
10
0
0
0
10
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _