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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLCD2 All Species: 9.39
Human Site: T28 Identified Species: 20.67
UniProt: A6NGC4 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NGC4 NP_001157879.1 264 28733 T28 W G L R R L P T P E S A A R D
Chimpanzee Pan troglodytes XP_001174204 437 46242 R201 E L G C L G D R P G P P P P P
Rhesus Macaque Macaca mulatta XP_001117332 467 50594 T231 W G L R R L P T P E L A A R D
Dog Lupus familis XP_853993 264 28572 T28 W A L Q L L P T P G S A A Q D
Cat Felis silvestris
Mouse Mus musculus Q8VC26 310 34121 P27 H W G L Q L L P T P K S V R D
Rat Rattus norvegicus Q5U2T1 247 28711 R20 L G A T L T F R A L R R V L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425399 241 27327 F14 L L L V A G S F V A F R L L N
Frog Xenopus laevis Q6GLX2 258 29536 T31 A I S P R L F T K Y S S T Y R
Zebra Danio Brachydanio rerio A8WGS4 246 28315 L19 S S V G F F K L V N Y G L G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493466 350 39805 L96 P E P D S R D L S A I P P N K
Sea Urchin Strong. purpuratus XP_789953 151 17363
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.2 53.3 77.6 N.A. 62.2 27.6 N.A. N.A. 43.5 25.3 34.4 N.A. N.A. N.A. 26 23.4
Protein Similarity: 100 56.9 54.5 85.2 N.A. 68.3 46.5 N.A. N.A. 59 42.4 57.9 N.A. N.A. N.A. 40.5 38.6
P-Site Identity: 100 6.6 93.3 66.6 N.A. 20 6.6 N.A. N.A. 6.6 26.6 0 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 6.6 93.3 80 N.A. 33.3 6.6 N.A. N.A. 13.3 33.3 6.6 N.A. N.A. N.A. 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 10 0 0 0 10 19 0 28 28 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 10 0 0 19 0 0 0 0 0 0 0 37 % D
% Glu: 10 10 0 0 0 0 0 0 0 19 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 10 19 10 0 0 10 0 0 0 0 % F
% Gly: 0 28 19 10 0 19 0 0 0 19 0 10 0 10 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 10 0 10 0 0 0 19 % K
% Leu: 19 19 37 10 28 46 10 19 0 10 10 0 19 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 10 % N
% Pro: 10 0 10 10 0 0 28 10 37 10 10 19 19 10 10 % P
% Gln: 0 0 0 10 10 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 19 28 10 0 19 0 0 10 19 0 28 10 % R
% Ser: 10 10 10 0 10 0 10 0 10 0 28 19 0 0 0 % S
% Thr: 0 0 0 10 0 10 0 37 10 0 0 0 10 0 0 % T
% Val: 0 0 10 10 0 0 0 0 19 0 0 0 19 0 0 % V
% Trp: 28 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 10 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _