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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF8L1
All Species:
15.76
Human Site:
T586
Identified Species:
34.67
UniProt:
A6NGE4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NGE4
NP_001017930.1
600
67373
T586
E
S
S
S
T
S
D
T
S
E
E
E
G
Q
D
Chimpanzee
Pan troglodytes
XP_528917
668
74962
T597
E
S
S
S
T
S
D
T
S
E
G
G
R
P
R
Rhesus Macaque
Macaca mulatta
XP_001093859
611
68308
T597
E
S
S
S
T
S
D
T
S
E
E
E
G
Q
D
Dog
Lupus familis
XP_536129
596
66580
S582
S
P
S
S
S
D
T
S
D
E
E
E
G
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8N7N5
591
66013
S577
S
P
S
S
S
D
T
S
D
E
E
E
G
P
D
Rat
Rattus norvegicus
Q5U2M6
591
66137
S577
S
P
S
S
S
D
T
S
D
E
E
E
G
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRH1
601
67089
D587
P
S
S
S
D
S
S
D
D
D
E
D
G
P
D
Zebra Danio
Brachydanio rerio
XP_001346262
607
66784
D593
W
S
S
P
E
S
S
D
E
E
D
G
G
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647657
748
83317
D728
R
N
S
N
S
S
D
D
T
N
D
E
G
A
D
Honey Bee
Apis mellifera
XP_392352
669
75650
D653
E
D
S
S
D
H
S
D
S
Q
S
E
G
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785904
416
46675
E403
S
D
S
D
E
T
S
E
S
S
E
D
L
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.2
89.5
67.1
N.A.
65.1
65.8
N.A.
N.A.
N.A.
60.7
51.7
N.A.
29.1
33.6
N.A.
38.1
Protein Similarity:
100
88.1
92.6
78
N.A.
78
77.8
N.A.
N.A.
N.A.
73.5
67.3
N.A.
45.9
53.8
N.A.
50.1
P-Site Identity:
100
66.6
100
46.6
N.A.
46.6
46.6
N.A.
N.A.
N.A.
46.6
40
N.A.
40
40
N.A.
20
P-Site Similarity:
100
66.6
100
60
N.A.
60
60
N.A.
N.A.
N.A.
60
46.6
N.A.
73.3
53.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
10
19
28
37
37
37
10
19
19
0
10
73
% D
% Glu:
37
0
0
0
19
0
0
10
10
64
64
64
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
19
82
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
10
28
0
10
0
0
0
0
0
0
0
0
0
64
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
19
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% R
% Ser:
37
46
100
73
37
55
37
28
46
10
10
0
0
0
0
% S
% Thr:
0
0
0
0
28
10
28
28
10
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _