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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF8L1
All Species:
30
Human Site:
Y446
Identified Species:
66
UniProt:
A6NGE4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NGE4
NP_001017930.1
600
67373
Y446
T
I
K
C
V
N
F
Y
G
P
R
S
E
F
V
Chimpanzee
Pan troglodytes
XP_528917
668
74962
Y457
T
I
K
C
V
N
F
Y
G
P
Q
S
E
F
V
Rhesus Macaque
Macaca mulatta
XP_001093859
611
68308
Y458
T
I
K
C
V
N
F
Y
G
P
R
S
E
F
V
Dog
Lupus familis
XP_536129
596
66580
Y442
T
V
K
G
V
N
F
Y
G
P
K
S
E
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8N7N5
591
66013
Y437
T
V
K
G
V
N
F
Y
G
P
K
S
E
F
V
Rat
Rattus norvegicus
Q5U2M6
591
66137
Y437
T
V
K
G
V
N
F
Y
G
P
K
S
E
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRH1
601
67089
Y446
T
V
K
G
V
N
F
Y
G
P
R
S
E
F
V
Zebra Danio
Brachydanio rerio
XP_001346262
607
66784
Y455
T
V
K
G
V
N
F
Y
G
P
C
S
E
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647657
748
83317
F573
T
I
K
G
V
N
F
F
G
P
R
S
E
Y
I
Honey Bee
Apis mellifera
XP_392352
669
75650
F505
T
V
K
G
V
N
F
F
G
P
K
S
E
F
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785904
416
46675
Q298
K
E
S
E
K
I
V
Q
Y
M
Q
G
D
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.2
89.5
67.1
N.A.
65.1
65.8
N.A.
N.A.
N.A.
60.7
51.7
N.A.
29.1
33.6
N.A.
38.1
Protein Similarity:
100
88.1
92.6
78
N.A.
78
77.8
N.A.
N.A.
N.A.
73.5
67.3
N.A.
45.9
53.8
N.A.
50.1
P-Site Identity:
100
93.3
100
80
N.A.
80
80
N.A.
N.A.
N.A.
86.6
80
N.A.
73.3
73.3
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
86.6
N.A.
93.3
93.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
28
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
10
0
10
0
0
0
0
0
0
0
0
91
0
0
% E
% Phe:
0
0
0
0
0
0
91
19
0
0
0
0
0
82
0
% F
% Gly:
0
0
0
64
0
0
0
0
91
0
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
37
0
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
91
0
10
0
0
0
0
0
37
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
91
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
91
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
19
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
0
91
0
0
0
% S
% Thr:
91
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
55
0
0
91
0
10
0
0
0
0
0
0
10
82
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
10
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _