KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF8L1
All Species:
4.24
Human Site:
Y539
Identified Species:
9.33
UniProt:
A6NGE4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NGE4
NP_001017930.1
600
67373
Y539
R
D
E
D
N
L
N
Y
T
D
S
F
D
N
R
Chimpanzee
Pan troglodytes
XP_528917
668
74962
Y550
R
D
E
D
N
L
N
Y
T
D
S
F
D
N
H
Rhesus Macaque
Macaca mulatta
XP_001093859
611
68308
H551
R
D
E
D
N
L
H
H
I
D
P
F
D
N
H
Dog
Lupus familis
XP_536129
596
66580
H535
R
D
E
D
S
L
H
H
T
D
L
F
D
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8N7N5
591
66013
H530
R
D
E
D
S
L
H
H
T
D
L
F
D
S
H
Rat
Rattus norvegicus
Q5U2M6
591
66137
H530
R
D
E
D
S
L
H
H
T
D
L
F
D
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NRH1
601
67089
H539
R
D
E
D
S
L
H
H
T
D
L
F
D
N
H
Zebra Danio
Brachydanio rerio
XP_001346262
607
66784
H548
R
D
E
D
N
V
R
H
G
D
Q
Y
D
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647657
748
83317
N671
S
I
D
L
D
I
N
N
F
Q
Y
F
I
R
G
Honey Bee
Apis mellifera
XP_392352
669
75650
E598
R
A
Q
E
T
T
T
E
S
D
A
F
D
R
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785904
416
46675
L379
L
R
F
L
M
A
H
L
R
H
R
A
R
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.2
89.5
67.1
N.A.
65.1
65.8
N.A.
N.A.
N.A.
60.7
51.7
N.A.
29.1
33.6
N.A.
38.1
Protein Similarity:
100
88.1
92.6
78
N.A.
78
77.8
N.A.
N.A.
N.A.
73.5
67.3
N.A.
45.9
53.8
N.A.
50.1
P-Site Identity:
100
93.3
66.6
60
N.A.
60
60
N.A.
N.A.
N.A.
66.6
46.6
N.A.
13.3
33.3
N.A.
0
P-Site Similarity:
100
93.3
80
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
86.6
73.3
N.A.
33.3
60
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
73
10
73
10
0
0
0
0
82
0
0
82
0
0
% D
% Glu:
0
0
73
10
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
10
0
0
82
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
55
55
0
10
0
0
0
0
55
% H
% Ile:
0
10
0
0
0
10
0
0
10
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
19
0
64
0
10
0
0
37
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
37
0
28
10
0
0
0
0
0
37
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
10
10
0
0
0
19
% Q
% Arg:
82
10
0
0
0
0
10
0
10
0
10
0
10
28
19
% R
% Ser:
10
0
0
0
37
0
0
0
10
0
19
0
0
28
0
% S
% Thr:
0
0
0
0
10
10
10
0
55
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
19
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _