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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL5C All Species: 31.52
Human Site: S145 Identified Species: 46.22
UniProt: A6NH57 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NH57 NP_001137440.1 179 20591 S145 I S H F L T L S T I K D H S W
Chimpanzee Pan troglodytes XP_001150533 354 38763 S145 I S H F L T L S T I K D H S W
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851644 179 20096 S145 I S Q F L T L S A I K D H P W
Cat Felis silvestris
Mouse Mus musculus Q6P068 179 20040 S145 I S Q F L T L S A I K D H P W
Rat Rattus norvegicus P51646 179 20695 T145 I S Q F L K L T S I K D H Q W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510998 179 20324 S145 I S K S L T L S S I K D H P W
Chicken Gallus gallus P26990 175 20078 T142 I Q E K L G L T R I R D R N W
Frog Xenopus laevis P51643 181 20696 H146 I T D K L G L H S L R H R N W
Zebra Danio Brachydanio rerio NP_956118 179 20470 S145 I Y K Y L T L S S I K D H P W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P61209 182 20669 H146 I T D K L G L H S L R N R N W
Honey Bee Apis mellifera XP_623433 179 20512 T145 I S R Q L D L T S I K K H Q W
Nematode Worm Caenorhab. elegans P34212 178 20015 L145 E V S T Q L G L Q T L R G A R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 N146 I T D K L G L N S L R Q R H W
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRC3 181 20574 H146 I T D K L G L H S L R Q R H W
Baker's Yeast Sacchar. cerevisiae P11076 181 20511 H146 I T E K L G L H S I R N R P W
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 S149 I T D K L G L S S L R Q R S W
Conservation
Percent
Protein Identity: 100 49.4 N.A. 82.6 N.A. 81.5 63.6 N.A. 68.7 39.1 40.3 68.1 N.A. 41.7 59.7 44.1 N.A.
Protein Similarity: 100 50 N.A. 87.1 N.A. 87.1 75.9 N.A. 77 62.5 61.3 77.6 N.A. 62.6 73.7 63.1 N.A.
P-Site Identity: 100 100 N.A. 80 N.A. 80 66.6 N.A. 73.3 40 26.6 66.6 N.A. 26.6 53.3 0 N.A.
P-Site Similarity: 100 100 N.A. 80 N.A. 80 80 N.A. 80 60 60 80 N.A. 66.6 66.6 6.6 N.A.
Percent
Protein Identity: N.A. 41.4 N.A. 40.8 40.8 42.7
Protein Similarity: N.A. 61.8 N.A. 61.3 60.7 61.6
P-Site Identity: N.A. 26.6 N.A. 26.6 33.3 40
P-Site Similarity: N.A. 60 N.A. 53.3 60 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 13 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 32 0 0 7 0 0 0 0 0 50 0 0 0 % D
% Glu: 7 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 32 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 44 7 0 0 0 0 0 7 0 0 % G
% His: 0 0 13 0 0 0 0 25 0 0 0 7 50 13 0 % H
% Ile: 94 0 0 0 0 0 0 0 0 63 0 0 0 0 0 % I
% Lys: 0 0 13 44 0 7 0 0 0 0 50 7 0 0 0 % K
% Leu: 0 0 0 0 94 7 94 7 0 32 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 13 0 19 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 32 0 % P
% Gln: 0 7 19 7 7 0 0 0 7 0 0 19 0 13 0 % Q
% Arg: 0 0 7 0 0 0 0 0 7 0 44 7 44 0 7 % R
% Ser: 0 44 7 7 0 0 0 44 63 0 0 0 0 19 0 % S
% Thr: 0 38 0 7 0 38 0 19 13 7 0 0 0 0 0 % T
% Val: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94 % W
% Tyr: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _