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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN8
All Species:
13.64
Human Site:
Y122
Identified Species:
30
UniProt:
A6NHC0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NHC0
NP_001137434
681
76665
Y122
T
L
N
E
E
L
L
Y
R
V
V
P
R
D
Q
Chimpanzee
Pan troglodytes
XP_510648
477
53512
Rhesus Macaque
Macaca mulatta
XP_001093975
475
53578
Dog
Lupus familis
XP_854850
828
91015
H215
T
L
N
Q
E
L
L
H
R
V
V
P
R
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91VA3
703
79316
Y122
T
L
N
E
K
L
L
Y
R
V
V
P
R
D
Q
Rat
Rattus norvegicus
Q78EJ9
703
79537
Y122
T
L
N
E
K
L
L
Y
R
V
L
P
R
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512324
758
85858
Y122
T
L
N
E
E
L
L
Y
R
V
V
P
R
N
Q
Chicken
Gallus gallus
Q92178
700
79210
A122
T
L
N
E
E
I
L
A
R
V
V
P
R
D
Q
Frog
Xenopus laevis
NP_001082012
702
79448
A122
T
L
E
P
D
L
V
A
Q
V
V
P
E
N
Q
Zebra Danio
Brachydanio rerio
NP_001013519
698
78325
A122
T
L
N
E
D
V
L
A
R
V
V
P
S
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q11002
828
93944
F160
T
Q
E
S
N
L
F
F
R
V
I
P
A
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.6
63
48.1
N.A.
71.8
71.6
N.A.
60.5
52.1
55.2
51.2
N.A.
34.5
N.A.
N.A.
N.A.
Protein Similarity:
100
65.6
64.7
57.3
N.A.
80.2
80.3
N.A.
69.7
68.8
72.6
70.3
N.A.
51.6
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
80
N.A.
93.3
86.6
N.A.
93.3
86.6
46.6
73.3
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
0
93.3
N.A.
100
100
N.A.
100
93.3
73.3
86.6
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
28
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
19
0
0
0
0
0
0
0
0
46
0
% D
% Glu:
0
0
19
55
37
0
0
0
0
0
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
73
0
0
0
64
64
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
64
0
10
0
0
0
0
0
0
0
0
19
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
82
0
0
0
% P
% Gln:
0
10
0
10
0
0
0
0
10
0
0
0
0
0
82
% Q
% Arg:
0
0
0
0
0
0
0
0
73
0
0
0
55
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
10
0
0
82
64
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _