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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OTOL1
All Species:
16.06
Human Site:
Y367
Identified Species:
39.26
UniProt:
A6NHN0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NHN0
NP_001073909.1
477
49422
Y367
I
K
F
E
K
I
L
Y
N
D
Q
G
N
Y
S
Chimpanzee
Pan troglodytes
XP_526369
456
47067
Y346
I
K
F
E
K
I
L
Y
N
D
Q
G
N
Y
S
Rhesus Macaque
Macaca mulatta
XP_001090663
333
34581
D224
S
D
V
P
I
K
F
D
K
I
L
Y
N
E
F
Dog
Lupus familis
XP_851299
333
34477
D224
S
D
V
P
I
K
F
D
K
I
L
Y
N
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q4ZJM7
482
49582
S372
I
K
F
D
K
I
L
S
N
D
Q
G
D
Y
S
Rat
Rattus norvegicus
Q5FVH0
243
25316
G134
R
V
L
L
N
E
Q
G
H
Y
D
A
T
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512453
478
50657
Y368
I
K
F
D
K
I
L
Y
N
E
Q
E
D
Y
N
Chicken
Gallus gallus
P08125
674
66415
S523
E
G
Y
V
K
G
E
S
R
E
L
S
G
M
S
Frog
Xenopus laevis
Q641F3
957
99741
T730
L
K
G
E
H
G
V
T
G
S
K
G
E
K
G
Zebra Danio
Brachydanio rerio
A5PN28
489
50773
I380
L
P
I
R
F
D
K
I
I
Y
N
E
E
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
37.1
36.2
N.A.
71.9
21.3
N.A.
65.9
32.9
23.4
46.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.3
48
46.9
N.A.
81.7
32.2
N.A.
75.7
44
31.1
57.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
80
0
N.A.
66.6
13.3
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
6.6
N.A.
93.3
6.6
N.A.
93.3
26.6
40
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
20
0
10
0
20
0
30
10
0
20
0
0
% D
% Glu:
10
0
0
30
0
10
10
0
0
20
0
20
20
20
0
% E
% Phe:
0
0
40
0
10
0
20
0
0
0
0
0
0
0
20
% F
% Gly:
0
10
10
0
0
20
0
10
10
0
0
40
10
0
20
% G
% His:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% H
% Ile:
40
0
10
0
20
40
0
10
10
20
0
0
0
0
0
% I
% Lys:
0
50
0
0
50
20
10
0
20
0
10
0
0
10
0
% K
% Leu:
20
0
10
10
0
0
40
0
0
0
30
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
10
0
0
0
40
0
10
0
40
0
10
% N
% Pro:
0
10
0
20
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
40
0
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
20
0
0
0
0
0
0
20
0
10
0
10
0
0
40
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
10
10
0
% T
% Val:
0
10
20
10
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
30
0
20
0
20
0
40
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _