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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYE2L
All Species:
5.15
Human Site:
S77
Identified Species:
18.89
UniProt:
A6NHP3
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NHP3
NP_001159811
258
31722
S77
W
D
K
D
L
R
V
S
D
K
Y
L
L
A
M
Chimpanzee
Pan troglodytes
XP_001143223
263
31944
K78
K
D
V
R
V
S
D
K
V
R
L
R
Q
P
L
Rhesus Macaque
Macaca mulatta
XP_001110275
431
50994
S162
E
E
P
E
K
A
L
S
P
E
P
E
E
T
W
Dog
Lupus familis
XP_851490
221
25643
R45
P
C
P
L
P
Q
S
R
G
R
K
R
D
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH6
268
30959
R56
S
P
Q
P
G
I
T
R
P
S
P
G
V
V
V
Rat
Rattus norvegicus
Q8R496
312
36205
A95
M
D
C
C
C
K
I
A
D
K
Y
L
L
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PU13
299
34670
S89
M
D
S
C
L
R
I
S
D
K
Y
L
I
A
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.2
27.6
20.1
N.A.
21.6
26.2
N.A.
N.A.
N.A.
28.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
85.1
38.2
34.5
N.A.
36.1
41.9
N.A.
N.A.
N.A.
43.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
0
N.A.
0
53.3
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
33.3
13.3
N.A.
20
73.3
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
15
0
0
0
0
0
43
0
% A
% Cys:
0
15
15
29
15
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
58
0
15
0
0
15
0
43
0
0
0
15
0
0
% D
% Glu:
15
15
0
15
0
0
0
0
0
15
0
15
15
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
0
0
0
15
0
0
15
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
29
0
0
0
0
0
15
15
0
% I
% Lys:
15
0
15
0
15
15
0
15
0
43
15
0
0
0
0
% K
% Leu:
0
0
0
15
29
0
15
0
0
0
15
43
29
0
15
% L
% Met:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
43
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
15
29
15
15
0
0
0
29
0
29
0
0
15
0
% P
% Gln:
0
0
15
0
0
15
0
0
0
0
0
0
15
0
0
% Q
% Arg:
0
0
0
15
0
29
0
29
0
29
0
29
0
0
0
% R
% Ser:
15
0
15
0
0
15
15
43
0
15
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
15
0
0
0
0
0
0
15
0
% T
% Val:
0
0
15
0
15
0
15
0
15
0
0
0
15
15
15
% V
% Trp:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _