Kinexus | PhosphoNET Evolution

Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.

Phosphosite		Conservation Score
Human Protein:	FBLL1	All Species:	5.76
Human Site:	S22	Identified Species:	9.05
UniProt:	A6NHQ2	Number Species:	14
		Phosphosite Substitution
		Charge Score:	0

Phosphosite
Sequences

Species

Species
Scientific Name

UniProt ID

NCBI Ref Seq ID

AA#

Mr(Da)

P-Site

-7

-6

-5

-4

-3

-2

-1

Human

Homo sapiens

A6NHQ2

NULL

333

34675

S22

Chimpanzee

Pan troglodytes

XP_001140427

308

32925

G22

Rhesus Macaque

Macaca mulatta

XP_001091930

335

34853

G22

Dog

Lupus familis

XP_546252

370

40576

G50

Cat

Felis silvestris

Mouse

Mus musculus

Q80WS3

314

33320

G51

Rat

Rattus norvegicus

P22509

327

34203

G22

Wallaby

Macropus eugenll

Platypus

Ornith. anatinus

XP_001517295

252

27451

Chicken

Gallus gallus

Frog

Xenopus laevis

P22232

323

34313

G22

Zebra Danio

Brachydanio rerio

Tiger Blowfish

Takifugu rubipres

Fruit Fly

Dros. melanogaster

Q9W1V3

344

34618

R23

Honey Bee

Apis mellifera

XP_624378

310

32283

S37

Nematode Worm

Caenorhab. elegans

Q22053

352

36364

D22

Sea Urchin

Strong. purpuratus

Poplar Tree

Populus trichocarpa

XP_002321930

245

26842

Maize

Zea mays

Rice

Oryza sativa

Thale Cress

Arabidopsis thaliana

Q94AH9

320

33635

S46

Baker's Yeast

Sacchar. cerevisiae

P15646

327

34447

A29

Red Bread Mold

Neurospora crassa

Q9HE26

323

33794

G48

Conservation
Percent
Protein Identity:	100	75	98.2	70.2	N.A.	85.5	78	N.A.	64.5	N.A.	72	N.A.	N.A.	70.9	70.8	64.4	N.A.
Protein Similarity:	100	82.5	98.5	73.2	N.A.	87.3	85.5	N.A.	70.5	N.A.	81.6	N.A.	N.A.	79	79.2	74.4	N.A.
P-Site Identity:	100	60	93.3	26.6	N.A.	60	46.6	N.A.	0	N.A.	33.3	N.A.	N.A.	53.3	66.6	53.3	N.A.
P-Site Similarity:	100	60	93.3	33.3	N.A.	60	46.6	N.A.	0	N.A.	40	N.A.	N.A.	53.3	66.6	53.3	N.A.


Percent
Protein Identity:	56.1	N.A.	N.A.	66.6	63.3	63
Protein Similarity:	64.2	N.A.	N.A.	78	74.7	75.6
P-Site Identity:	0	N.A.	N.A.	60	60	60
P-Site Similarity:	0	N.A.	N.A.	60	66.6	60

Phosphosite Consensus
Position	-7	-6	-5	-4	-3	-4	-5	0	+1	+2	+3	+4	+5	+6	+7
% Ala:	0	0	0	0	7	0	0	7	0	0	0	0	0	0	0	% A
% Cys:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% C
% Asp:	0	7	0	0	0	14	0	7	7	7	0	0	0	7	0	% D
% Glu:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% E
% Phe:	7	0	0	14	0	7	14	0	7	0	0	7	0	0	0	% F
% Gly:	20	67	74	60	47	34	47	47	34	47	80	60	34	67	67	% G
% His:	0	0	0	0	0	0	7	0	0	0	0	0	0	0	0	% H
% Ile:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% I
% Lys:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% K
% Leu:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% L
% Met:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% M
% Asn:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% N
% Pro:	0	7	0	0	0	7	0	0	0	0	0	7	0	0	0	% P
% Gln:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% Q
% Arg:	60	7	14	0	27	7	20	7	27	34	0	0	54	7	20	% R
% Ser:	0	0	0	7	7	0	0	20	0	0	0	14	0	0	0	% S
% Thr:	0	0	0	0	0	0	0	0	0	0	7	0	0	0	0	% T
% Val:	0	0	0	7	0	7	0	0	0	0	0	0	0	7	0	% V
% Trp:	0	0	0	0	0	14	0	0	14	0	0	0	0	0	0	% W
% Tyr:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% Y
% Spaces:	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	% _