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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMCHD1 All Species: 16.97
Human Site: S1520 Identified Species: 41.48
UniProt: A6NHR9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NHR9 NP_056110.2 2005 226374 S1520 L V R D L H L S I T D D Y D N
Chimpanzee Pan troglodytes XP_512045 2005 226402 S1520 L V R D L H L S I T D E Y D N
Rhesus Macaque Macaca mulatta XP_001086253 1365 152814 P948 P K I K P P T P A V S N V R S
Dog Lupus familis XP_547657 2003 226563 T1525 L V R D L H L T I T D D Y N N
Cat Felis silvestris
Mouse Mus musculus Q6P5D8 2007 225630 S1521 L V K D L R L S I T D N Y G N
Rat Rattus norvegicus XP_001056555 2006 226030 S1520 L V K D L R L S I T D N Y G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508602 1277 142834 L860 S I V M Y R N L F D A G N Q L
Chicken Gallus gallus XP_419144 1794 203200 E1365 P A L K K P L E P Y R L S F M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_699397 1203 136319 Q786 G K Y T L H L Q T K L S D S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788327 2012 226821 A1524 Q S R T L I K A L K L Q L V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 66.6 91.3 N.A. 86.5 88 N.A. 47.2 66.5 N.A. 31.8 N.A. N.A. N.A. N.A. 44.8
Protein Similarity: 100 99.7 67.2 95 N.A. 93.5 94.2 N.A. 54.4 77.1 N.A. 44 N.A. N.A. N.A. N.A. 64.2
P-Site Identity: 100 93.3 0 86.6 N.A. 73.3 73.3 N.A. 0 6.6 N.A. 20 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 13.3 100 N.A. 86.6 86.6 N.A. 6.6 6.6 N.A. 26.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 10 10 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 50 0 0 0 0 0 10 50 20 10 20 10 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 10 0 20 0 % G
% His: 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 0 10 0 0 50 0 0 0 0 0 0 % I
% Lys: 0 20 20 20 10 0 10 0 0 20 0 0 0 0 0 % K
% Leu: 50 0 10 0 70 0 70 10 10 0 20 10 10 0 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 30 10 10 50 % N
% Pro: 20 0 0 0 10 20 0 10 10 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 10 0 0 0 10 0 10 0 % Q
% Arg: 0 0 40 0 0 30 0 0 0 0 10 0 0 10 0 % R
% Ser: 10 10 0 0 0 0 0 40 0 0 10 10 10 10 20 % S
% Thr: 0 0 0 20 0 0 10 10 10 50 0 0 0 0 0 % T
% Val: 0 50 10 0 0 0 0 0 0 10 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 10 0 0 0 0 10 0 0 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _