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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMX3
All Species:
14.24
Human Site:
S143
Identified Species:
26.11
UniProt:
A6NHT5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NHT5
NP_001099044.1
357
37825
S143
E
K
A
L
L
R
D
S
S
P
A
S
G
T
D
Chimpanzee
Pan troglodytes
XP_508090
720
76742
S506
E
K
A
L
L
R
D
S
S
P
A
S
G
T
D
Rhesus Macaque
Macaca mulatta
XP_001105231
273
29541
E75
P
D
P
H
G
P
K
E
Q
G
P
K
H
H
P
Dog
Lupus familis
XP_853978
893
95948
S680
E
K
A
L
L
R
D
S
S
P
A
S
G
T
D
Cat
Felis silvestris
Mouse
Mus musculus
P42581
356
37868
S143
E
K
A
L
L
R
D
S
S
P
A
S
G
T
D
Rat
Rattus norvegicus
O88181
384
41445
L125
P
Q
S
A
A
Q
Q
L
G
S
A
A
A
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517986
237
25439
R39
E
L
G
H
G
E
P
R
S
Q
S
N
A
C
P
Chicken
Gallus gallus
O57601
308
33768
S110
R
T
E
A
A
E
K
S
L
L
R
D
S
S
P
Frog
Xenopus laevis
Q8JJ64
306
34004
L108
V
P
D
K
S
L
L
L
G
P
T
S
P
V
S
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
K99
H
R
T
E
A
A
Q
K
A
R
D
S
S
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
N338
S
P
N
N
N
N
N
N
S
N
T
T
A
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
Sea Urchin
Strong. purpuratus
Q26656
405
44721
F170
A
W
M
H
G
A
S
F
L
H
Y
H
G
M
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.5
33.8
38.7
N.A.
95.5
23.7
N.A.
40.9
72.2
65.2
64.9
N.A.
29.7
N.A.
22.1
29.1
Protein Similarity:
100
49.5
46.5
39.3
N.A.
96.6
35.1
N.A.
48.7
76.1
72.2
72.2
N.A.
37.8
N.A.
29.9
40.2
P-Site Identity:
100
100
0
100
N.A.
100
6.6
N.A.
13.3
6.6
13.3
6.6
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
0
100
N.A.
100
33.3
N.A.
26.6
13.3
13.3
20
N.A.
33.3
N.A.
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
31
16
24
16
0
0
8
0
39
8
24
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
8
0
0
0
31
0
0
0
8
8
0
0
31
% D
% Glu:
39
0
8
8
0
16
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
24
0
0
0
16
8
0
0
39
0
0
% G
% His:
8
0
0
24
0
0
0
0
0
8
0
8
8
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
31
0
8
0
0
16
8
0
0
0
8
0
0
0
% K
% Leu:
0
8
0
31
31
8
8
16
16
8
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
8
8
8
8
8
0
8
0
8
0
0
0
% N
% Pro:
16
16
8
0
0
8
8
0
0
39
8
0
8
8
39
% P
% Gln:
0
8
0
0
0
8
16
0
8
8
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
31
0
8
0
8
8
0
0
0
0
% R
% Ser:
8
0
8
0
8
0
8
39
47
8
8
47
16
16
16
% S
% Thr:
0
8
8
0
0
0
0
0
0
0
16
8
0
31
8
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _