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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMX3
All Species:
15.15
Human Site:
S182
Identified Species:
27.78
UniProt:
A6NHT5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NHT5
NP_001099044.1
357
37825
S182
I
I
L
E
E
S
D
S
E
E
S
K
K
E
G
Chimpanzee
Pan troglodytes
XP_508090
720
76742
S545
I
I
L
E
E
S
D
S
E
E
S
K
K
E
G
Rhesus Macaque
Macaca mulatta
XP_001105231
273
29541
H113
T
S
F
L
S
P
S
H
S
D
F
K
E
E
K
Dog
Lupus familis
XP_853978
893
95948
S719
I
I
L
E
E
S
D
S
E
E
G
K
K
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P42581
356
37868
S182
I
I
L
E
E
S
D
S
E
E
G
K
K
E
G
Rat
Rattus norvegicus
O88181
384
41445
E184
E
S
F
R
P
K
L
E
Q
E
D
S
K
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517986
237
25439
E77
G
Q
G
R
R
P
G
E
A
G
P
G
P
G
G
Chicken
Gallus gallus
O57601
308
33768
I148
D
P
K
S
P
A
E
I
V
L
E
E
S
D
S
Frog
Xenopus laevis
Q8JJ64
306
34004
I146
S
K
S
P
E
E
I
I
L
E
E
S
D
P
E
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
I137
D
N
K
S
G
D
E
I
V
L
E
E
G
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
S423
P
H
P
H
L
T
G
S
H
G
G
Y
L
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
Sea Urchin
Strong. purpuratus
Q26656
405
44721
S208
I
S
P
R
P
T
Q
S
H
S
S
F
G
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.5
33.8
38.7
N.A.
95.5
23.7
N.A.
40.9
72.2
65.2
64.9
N.A.
29.7
N.A.
22.1
29.1
Protein Similarity:
100
49.5
46.5
39.3
N.A.
96.6
35.1
N.A.
48.7
76.1
72.2
72.2
N.A.
37.8
N.A.
29.9
40.2
P-Site Identity:
100
100
13.3
93.3
N.A.
93.3
13.3
N.A.
6.6
0
13.3
0
N.A.
6.6
N.A.
0
26.6
P-Site Similarity:
100
100
26.6
93.3
N.A.
93.3
20
N.A.
6.6
26.6
13.3
20
N.A.
13.3
N.A.
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
8
31
0
0
8
8
0
8
16
0
% D
% Glu:
8
0
0
31
39
8
16
16
31
47
24
16
8
47
16
% E
% Phe:
0
0
16
0
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
8
0
8
0
8
0
16
0
0
16
24
8
16
8
39
% G
% His:
0
8
0
8
0
0
0
8
16
0
0
0
0
0
0
% H
% Ile:
39
31
0
0
0
0
8
24
0
0
0
0
0
0
0
% I
% Lys:
0
8
16
0
0
8
0
0
0
0
0
39
39
0
16
% K
% Leu:
0
0
31
8
8
0
8
0
8
16
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
16
8
24
16
0
0
0
0
8
0
8
8
8
% P
% Gln:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
24
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
24
8
16
8
31
8
47
8
8
24
16
8
0
8
% S
% Thr:
8
0
0
0
0
16
0
0
0
0
0
0
0
8
8
% T
% Val:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _