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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMX3
All Species:
27.88
Human Site:
T245
Identified Species:
51.11
UniProt:
A6NHT5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NHT5
NP_001099044.1
357
37825
T245
Q
V
F
Q
L
E
S
T
F
D
M
K
R
Y
L
Chimpanzee
Pan troglodytes
XP_508090
720
76742
T608
Q
V
F
Q
L
E
S
T
F
D
M
K
R
Y
L
Rhesus Macaque
Macaca mulatta
XP_001105231
273
29541
S176
D
M
K
R
Y
L
S
S
S
E
R
A
C
L
A
Dog
Lupus familis
XP_853978
893
95948
T782
Q
V
F
Q
L
E
S
T
F
D
M
K
R
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
P42581
356
37868
T245
Q
V
F
Q
L
E
S
T
F
D
M
K
R
Y
L
Rat
Rattus norvegicus
O88181
384
41445
S247
Q
L
N
Q
L
E
R
S
F
E
R
Q
K
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517986
237
25439
L140
R
A
G
L
A
A
S
L
Q
L
T
E
T
Q
V
Chicken
Gallus gallus
O57601
308
33768
R211
R
Y
L
S
S
S
E
R
A
G
L
A
A
S
L
Frog
Xenopus laevis
Q8JJ64
306
34004
A209
Y
L
S
S
S
E
R
A
G
L
A
A
S
L
H
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
R200
R
Y
L
S
S
S
E
R
A
G
L
A
A
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
T486
Q
V
F
Q
L
E
S
T
F
D
L
K
R
Y
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
C50
E
I
D
E
F
G
R
C
K
S
S
L
D
Q
A
Sea Urchin
Strong. purpuratus
Q26656
405
44721
T271
Q
V
F
Q
L
E
S
T
F
E
V
K
R
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.5
33.8
38.7
N.A.
95.5
23.7
N.A.
40.9
72.2
65.2
64.9
N.A.
29.7
N.A.
22.1
29.1
Protein Similarity:
100
49.5
46.5
39.3
N.A.
96.6
35.1
N.A.
48.7
76.1
72.2
72.2
N.A.
37.8
N.A.
29.9
40.2
P-Site Identity:
100
100
6.6
100
N.A.
100
46.6
N.A.
6.6
6.6
6.6
6.6
N.A.
93.3
N.A.
0
86.6
P-Site Similarity:
100
100
33.3
100
N.A.
100
80
N.A.
26.6
20
13.3
20
N.A.
100
N.A.
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
8
16
0
8
31
16
0
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
39
0
0
8
0
0
% D
% Glu:
8
0
0
8
0
62
16
0
0
24
0
8
0
0
0
% E
% Phe:
0
0
47
0
8
0
0
0
54
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
0
0
8
16
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
8
0
0
47
8
0
0
% K
% Leu:
0
16
16
8
54
8
0
8
0
16
24
8
0
16
70
% L
% Met:
0
8
0
0
0
0
0
0
0
0
31
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
54
0
0
54
0
0
0
0
8
0
0
8
0
16
0
% Q
% Arg:
24
0
0
8
0
0
24
16
0
0
16
0
47
0
0
% R
% Ser:
0
0
8
24
24
16
62
16
8
8
8
0
8
16
0
% S
% Thr:
0
0
0
0
0
0
0
47
0
0
8
0
8
0
0
% T
% Val:
0
47
0
0
0
0
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
16
0
0
8
0
0
0
0
0
0
0
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _