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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 15.45
Human Site: S441 Identified Species: 42.5
UniProt: A6NHZ5 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NHZ5 NP_001073947 511 56410 S441 P Q D E L A M S K F N Q Q K Y
Chimpanzee Pan troglodytes XP_517600 514 56800 S444 P Q D E L A M S K F D Q Q K Y
Rhesus Macaque Macaca mulatta XP_001094307 493 54555 H428 A E L R T V V H P F P V D C Y
Dog Lupus familis XP_545199 510 56484 S440 P Q D D L A M S K F D Q Q K Y
Cat Felis silvestris
Mouse Mus musculus Q3UJB3 510 56525 S440 P Q D E L S V S K F D Q Q K Y
Rat Rattus norvegicus Q569B5 493 54896 A408 Y G N P L S M A G L K E L L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513278 516 57697 P446 P L D D S S L P N F D H Q K Y
Chicken Gallus gallus
Frog Xenopus laevis Q640Z9 509 57042 Y444 P E L H L V V Y P F P V D C Y
Zebra Danio Brachydanio rerio Q1L8H0 526 59513 V447 P L D D R T L V N Y D S D K F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 33.2 80.6 N.A. 79.8 31.5 N.A. 61.8 N.A. 32 43.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 51 87.8 N.A. 88.6 49.9 N.A. 79.6 N.A. 52.8 60.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 13.3 86.6 N.A. 80 13.3 N.A. 40 N.A. 26.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 40 N.A. 66.6 N.A. 40 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 34 0 12 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 0 % C
% Asp: 0 0 67 34 0 0 0 0 0 0 56 0 34 0 0 % D
% Glu: 0 23 0 34 0 0 0 0 0 0 0 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 78 0 0 0 0 12 % F
% Gly: 0 12 0 0 0 0 0 0 12 0 0 0 0 0 0 % G
% His: 0 0 0 12 0 0 0 12 0 0 0 12 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 45 0 12 0 0 67 0 % K
% Leu: 0 23 23 0 67 0 23 0 0 12 0 0 12 12 0 % L
% Met: 0 0 0 0 0 0 45 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 23 0 12 0 0 0 0 % N
% Pro: 78 0 0 12 0 0 0 12 23 0 23 0 0 0 0 % P
% Gln: 0 45 0 0 0 0 0 0 0 0 0 45 56 0 0 % Q
% Arg: 0 0 0 12 12 0 0 0 0 0 0 0 0 0 12 % R
% Ser: 0 0 0 0 12 34 0 45 0 0 0 12 0 0 0 % S
% Thr: 0 0 0 0 12 12 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 23 34 12 0 0 0 23 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 0 0 12 0 12 0 0 0 0 78 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _