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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM8C All Species: 17.88
Human Site: Y118 Identified Species: 65.56
UniProt: A6NI61 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NI61 NP_001073952.1 221 24699 Y118 D R W G Y G V Y S G P I G T A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100936 217 24018 I118 Y G V Y S G P I G T A I L I I
Dog Lupus familis XP_548396 410 44620 Y307 D R W G Y G V Y S G P I G T A
Cat Felis silvestris
Mouse Mus musculus Q9D1N4 221 24774 Y118 D R W G Y G V Y S G P I G T A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505223 221 24840 Y118 D R W G Y G V Y S G P I G T A
Chicken Gallus gallus XP_001236919 88 10071
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6IQ69 220 24733 Y118 D R L G Y G I Y S G P I G T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 85.5 51.7 N.A. 88.6 N.A. N.A. 90 36.2 N.A. 75.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 88.6 52.9 N.A. 93.6 N.A. N.A. 96.3 38 N.A. 87.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 13.3 100 N.A. 100 N.A. N.A. 100 0 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 13.3 100 N.A. 100 N.A. N.A. 100 0 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 72 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 72 0 86 0 0 15 72 0 0 72 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 15 15 0 0 0 86 0 15 15 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 15 0 0 0 0 0 0 0 0 0 15 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 15 0 0 0 72 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 15 0 0 0 72 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 15 0 0 0 72 0 % T
% Val: 0 0 15 0 0 0 58 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 15 72 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _