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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM8C
All Species:
17.88
Human Site:
Y118
Identified Species:
65.56
UniProt:
A6NI61
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NI61
NP_001073952.1
221
24699
Y118
D
R
W
G
Y
G
V
Y
S
G
P
I
G
T
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100936
217
24018
I118
Y
G
V
Y
S
G
P
I
G
T
A
I
L
I
I
Dog
Lupus familis
XP_548396
410
44620
Y307
D
R
W
G
Y
G
V
Y
S
G
P
I
G
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1N4
221
24774
Y118
D
R
W
G
Y
G
V
Y
S
G
P
I
G
T
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505223
221
24840
Y118
D
R
W
G
Y
G
V
Y
S
G
P
I
G
T
A
Chicken
Gallus gallus
XP_001236919
88
10071
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6IQ69
220
24733
Y118
D
R
L
G
Y
G
I
Y
S
G
P
I
G
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
85.5
51.7
N.A.
88.6
N.A.
N.A.
90
36.2
N.A.
75.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
88.6
52.9
N.A.
93.6
N.A.
N.A.
96.3
38
N.A.
87.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
100
N.A.
100
N.A.
N.A.
100
0
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
N.A.
N.A.
100
0
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
72
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
0
72
0
86
0
0
15
72
0
0
72
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
15
15
0
0
0
86
0
15
15
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
0
0
0
0
0
0
0
0
0
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
15
0
0
0
72
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
15
0
0
0
72
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
15
0
0
0
72
0
% T
% Val:
0
0
15
0
0
0
58
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
15
72
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _