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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 4.85
Human Site: S112 Identified Species: 8.21
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S112 L Q L S L R K S E L F P A A R
Chimpanzee Pan troglodytes XP_001156388 511 54866 S19 G P G P G R G S W G R I Y A R
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 L86 E A C F W P G L G D L G K A T
Dog Lupus familis XP_541912 655 69604 A100 I R Q P V D G A A K P P L A S
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235
Rat Rattus norvegicus Q5U2Z2 548 58063 K56 S G L G G P R K S G H R G A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 S119 P P L A S L V S G S G V L A G
Chicken Gallus gallus Q5F464 604 65121 A86 G N I T S Q G A F P P P P P L
Frog Xenopus laevis A9LS46 690 75317 V97 E G I Y K S D V A L P C Y S G
Zebra Danio Brachydanio rerio A8DZE6 648 70883 T111 S D R L R R Y T H A E V Q G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 H116 R P V E Q I Q H T H N G S A Q
Honey Bee Apis mellifera XP_391978 881 97801 A122 N R M S H Q Q A P V Y E N I D
Nematode Worm Caenorhab. elegans Q09476 413 46434
Sea Urchin Strong. purpuratus XP_792799 904 97329 S183 G R E S Y D R S V I S R N S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 26.6 6.6 13.3 N.A. 0 13.3 N.A. 20 6.6 6.6 6.6 N.A. 6.6 6.6 0 13.3
P-Site Similarity: 100 26.6 6.6 40 N.A. 0 20 N.A. 26.6 33.3 20 13.3 N.A. 33.3 53.3 0 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 22 15 8 0 0 8 50 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 8 0 0 0 15 8 0 0 8 0 0 0 0 8 % D
% Glu: 15 0 8 8 0 0 0 0 8 0 8 8 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 8 0 8 0 0 0 0 % F
% Gly: 22 15 8 8 15 0 29 0 15 15 8 15 8 8 15 % G
% His: 0 0 0 0 8 0 0 8 8 8 8 0 0 0 8 % H
% Ile: 8 0 15 0 0 8 0 0 0 8 0 8 0 8 0 % I
% Lys: 0 0 0 0 8 0 8 8 0 8 0 0 8 0 0 % K
% Leu: 8 0 22 8 8 8 0 8 0 15 8 0 15 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 0 0 0 8 0 15 0 8 % N
% Pro: 8 22 0 15 0 15 0 0 8 8 22 22 8 8 0 % P
% Gln: 0 8 8 0 8 15 15 0 0 0 0 0 8 0 8 % Q
% Arg: 8 22 8 0 8 22 15 0 0 0 8 15 0 0 15 % R
% Ser: 15 0 0 22 15 8 0 29 8 8 8 0 8 15 15 % S
% Thr: 0 0 0 8 0 0 0 8 8 0 0 0 0 0 8 % T
% Val: 0 0 8 0 8 0 8 8 8 8 0 15 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 8 0 0 0 8 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _