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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 5.45
Human Site: S130 Identified Species: 9.23
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S130 R P A D P G L S P R C L R R P
Chimpanzee Pan troglodytes XP_001156388 511 54866 G34 R T V F L G A G R A K R R G F
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 T101 Q R E D Q S A T N P L L A L G
Dog Lupus familis XP_541912 655 69604 E119 Q P A C P P P E Q R A R P P A
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235
Rat Rattus norvegicus Q5U2Z2 548 58063 L71 G G P G D E A L E P A R E Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 P141 G P N P P P V P Q G Q R A K M
Chicken Gallus gallus Q5F464 604 65121 T108 Q V N P G G K T L E E R R S S
Frog Xenopus laevis A9LS46 690 75317 S124 Y R H S C G N S F E G V P I S
Zebra Danio Brachydanio rerio A8DZE6 648 70883 Y126 R Y S T G C A Y D G L V L G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 S142 R I A P Q K H S P V Y E N L E
Honey Bee Apis mellifera XP_391978 881 97801 R169 E S Y E P T F R K A Q P Q V P
Nematode Worm Caenorhab. elegans Q09476 413 46434
Sea Urchin Strong. purpuratus XP_792799 904 97329 P207 W I T D D L C P P R S V A Q T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 20 13.3 26.6 N.A. 0 0 N.A. 13.3 13.3 13.3 6.6 N.A. 26.6 13.3 0 20
P-Site Similarity: 100 20 26.6 33.3 N.A. 0 6.6 N.A. 26.6 26.6 20 20 N.A. 26.6 26.6 0 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 22 0 0 0 29 0 0 15 15 0 22 0 8 % A
% Cys: 0 0 0 8 8 8 8 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 22 15 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 8 0 8 8 0 8 0 8 8 15 8 8 8 0 8 % E
% Phe: 0 0 0 8 0 0 8 0 8 0 0 0 0 0 8 % F
% Gly: 15 8 0 8 15 29 0 8 0 15 8 0 0 15 15 % G
% His: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 8 8 0 8 0 8 0 0 8 8 % K
% Leu: 0 0 0 0 8 8 8 8 8 0 15 15 8 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 15 0 0 0 8 0 8 0 0 0 8 0 0 % N
% Pro: 0 22 8 22 29 15 8 15 22 15 0 8 15 8 15 % P
% Gln: 22 0 0 0 15 0 0 0 15 0 15 0 8 15 0 % Q
% Arg: 29 15 0 0 0 0 0 8 8 22 0 36 22 8 0 % R
% Ser: 0 8 8 8 0 8 0 22 0 0 8 0 0 8 15 % S
% Thr: 0 8 8 8 0 8 0 15 0 0 0 0 0 0 8 % T
% Val: 0 8 8 0 0 0 8 0 0 8 0 22 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 8 0 0 0 0 8 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _