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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 5.76
Human Site: S163 Identified Species: 9.74
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S163 P P P L P P H S R G R S A V S
Chimpanzee Pan troglodytes XP_001156388 511 54866 C65 G K G D G A G C G E R C R L L
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 G132 H G P G P G R G S W G R I C A
Dog Lupus familis XP_541912 655 69604 P159 Q P G P C E D P A C L T H G D
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235
Rat Rattus norvegicus Q5U2Z2 548 58063 G102 F E G S F P G G P P P T R A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 P195 G P G F P C L P H G S Y Y D S
Chicken Gallus gallus Q5F464 604 65121 Q141 S P Y K P R I Q Q G S G T S S
Frog Xenopus laevis A9LS46 690 75317 S162 S P R S S M A S S A S S S Q E
Zebra Danio Brachydanio rerio A8DZE6 648 70883 T157 P D G R Y T A T S P R S S L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 L174 G S R Q S A I L N G Y L L M Q
Honey Bee Apis mellifera XP_391978 881 97801 Y223 G P Q V P P N Y Y H P A T I N
Nematode Worm Caenorhab. elegans Q09476 413 46434
Sea Urchin Strong. purpuratus XP_792799 904 97329 H238 H V S G T S L H R N D Q T V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 6.6 13.3 6.6 N.A. 0 6.6 N.A. 26.6 26.6 20 20 N.A. 6.6 20 0 13.3
P-Site Similarity: 100 13.3 20 13.3 N.A. 0 13.3 N.A. 26.6 33.3 26.6 46.6 N.A. 13.3 53.3 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 15 15 0 8 8 0 8 8 8 15 % A
% Cys: 0 0 0 0 8 8 0 8 0 8 0 8 0 8 0 % C
% Asp: 0 8 0 8 0 0 8 0 0 0 8 0 0 8 8 % D
% Glu: 0 8 0 0 0 8 0 0 0 8 0 0 0 0 8 % E
% Phe: 8 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 29 8 36 15 8 8 15 15 8 29 8 8 0 8 0 % G
% His: 15 0 0 0 0 0 8 8 8 8 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 15 0 0 0 0 0 8 8 0 % I
% Lys: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 8 0 0 15 8 0 0 8 8 8 15 15 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 8 0 8 8 0 0 0 0 8 % N
% Pro: 15 43 15 8 36 22 0 15 8 15 15 0 0 0 0 % P
% Gln: 8 0 8 8 0 0 0 8 8 0 0 8 0 8 8 % Q
% Arg: 0 0 15 8 0 8 8 0 15 0 22 8 15 0 0 % R
% Ser: 15 8 8 15 15 8 0 15 22 0 22 22 15 8 22 % S
% Thr: 0 0 0 0 8 8 0 8 0 0 0 15 22 0 0 % T
% Val: 0 8 0 8 0 0 0 0 0 0 0 0 0 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 0 8 8 0 8 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _