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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 4.55
Human Site: S180 Identified Species: 7.69
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S180 A F L P P Q R S P S A P R E A
Chimpanzee Pan troglodytes XP_001156388 511 54866 L82 L R P G W R Q L P P A Q P A E
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 Q149 T V F P G V G Q A Q R L G L Q
Dog Lupus familis XP_541912 655 69604 P176 D N V P L P S P K W A D Q P G
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235
Rat Rattus norvegicus Q5U2Z2 548 58063 F119 P L S S P P D F R L E T T A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 E212 P P G S E W G E E P G Q F T G
Chicken Gallus gallus Q5F464 604 65121 T158 A T T P S V S T P V T G H K R
Frog Xenopus laevis A9LS46 690 75317 S179 K Y S S P R S S I S S N A L S
Zebra Danio Brachydanio rerio A8DZE6 648 70883 K174 H S S Q D Q S K H T S P R S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 T191 R A G R F A H T P V P E N Q G
Honey Bee Apis mellifera XP_391978 881 97801 K240 D Y V V M T G K V G Q T Q N Q
Nematode Worm Caenorhab. elegans Q09476 413 46434
Sea Urchin Strong. purpuratus XP_792799 904 97329 R255 A A L D D R R R D F H H Q R D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 13.3 6.6 13.3 N.A. 0 6.6 N.A. 0 20 20 20 N.A. 6.6 0 0 20
P-Site Similarity: 100 26.6 6.6 26.6 N.A. 0 6.6 N.A. 0 33.3 46.6 40 N.A. 20 20 0 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 15 0 0 0 8 0 0 8 0 22 0 8 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 8 15 0 8 0 8 0 0 8 0 0 8 % D
% Glu: 0 0 0 0 8 0 0 8 8 0 8 8 0 8 8 % E
% Phe: 0 8 8 0 8 0 0 8 0 8 0 0 8 0 0 % F
% Gly: 0 0 15 8 8 0 22 0 0 8 8 8 8 0 22 % G
% His: 8 0 0 0 0 0 8 0 8 0 8 8 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 15 8 0 0 0 0 8 0 % K
% Leu: 8 8 15 0 8 0 0 8 0 8 0 8 0 15 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 8 8 8 0 % N
% Pro: 15 8 8 29 22 15 0 8 29 15 8 15 8 8 8 % P
% Gln: 0 0 0 8 0 15 8 8 0 8 8 15 22 8 15 % Q
% Arg: 8 8 0 8 0 22 15 8 8 0 8 0 15 8 8 % R
% Ser: 0 8 22 22 8 0 29 15 0 15 15 0 0 8 15 % S
% Thr: 8 8 8 0 0 8 0 15 0 8 8 15 8 8 0 % T
% Val: 0 8 15 8 0 15 0 0 8 15 0 0 0 0 0 % V
% Trp: 0 0 0 0 8 8 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _