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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WTIP
All Species:
13.33
Human Site:
S228
Identified Species:
22.56
UniProt:
A6NIX2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NIX2
NP_001073905
654
67454
S228
A
G
R
A
M
Q
R
S
R
A
G
A
D
E
A
Chimpanzee
Pan troglodytes
XP_001156388
511
54866
R128
P
G
L
H
A
P
P
R
S
R
R
S
A
A
A
Rhesus Macaque
Macaca mulatta
XP_001110152
578
62790
Q195
S
L
Q
A
G
W
R
Q
L
P
P
A
Q
P
A
Dog
Lupus familis
XP_541912
655
69604
S223
Y
Q
P
P
L
S
P
S
S
A
K
S
F
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQJ8
398
42235
A11
S
R
T
A
A
D
D
A
A
L
L
L
A
G
L
Rat
Rattus norvegicus
Q5U2Z2
548
58063
S165
G
A
S
G
A
G
G
S
R
P
C
S
N
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513540
700
74650
S260
T
L
N
S
Y
R
S
S
E
S
G
Y
S
S
L
Chicken
Gallus gallus
Q5F464
604
65121
S207
K
P
Q
P
V
P
A
S
Y
T
T
A
S
T
P
Frog
Xenopus laevis
A9LS46
690
75317
S225
G
G
V
L
S
P
R
S
S
Y
A
S
T
T
S
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
T222
S
K
H
S
S
P
R
T
S
L
N
S
Y
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572930
728
77943
A246
I
P
H
S
G
Q
R
A
Q
P
Q
A
S
P
A
Honey Bee
Apis mellifera
XP_391978
881
97801
S289
A
S
R
Y
L
Q
G
S
S
S
S
L
D
H
Q
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
R30
Q
H
T
T
E
V
L
R
R
A
H
I
S
D
R
Sea Urchin
Strong. purpuratus
XP_792799
904
97329
S302
S
P
A
G
S
Q
R
S
S
I
A
S
N
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
46.6
38.3
N.A.
55.9
37.9
N.A.
37.4
28.5
41.2
41.2
N.A.
33
32.1
20.1
29.2
Protein Similarity:
100
65.5
52.7
47
N.A.
57.4
46.7
N.A.
47.8
40.2
51.7
50.7
N.A.
44.3
42.2
31.7
39.4
P-Site Identity:
100
13.3
26.6
20
N.A.
6.6
13.3
N.A.
13.3
13.3
20
6.6
N.A.
26.6
33.3
13.3
20
P-Site Similarity:
100
20
40
40
N.A.
20
26.6
N.A.
33.3
26.6
33.3
40
N.A.
46.6
46.6
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
22
22
0
8
15
8
22
15
29
15
8
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% C
% Asp:
0
0
0
0
0
8
8
0
0
0
0
0
15
15
0
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
15
22
0
15
15
8
15
0
0
0
15
0
0
8
0
% G
% His:
0
8
15
8
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% I
% Lys:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
15
8
8
15
0
8
0
8
15
8
15
0
0
15
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
8
0
15
0
0
% N
% Pro:
8
22
8
15
0
29
15
0
0
22
8
0
0
15
8
% P
% Gln:
8
8
15
0
0
29
0
8
8
0
8
0
8
0
8
% Q
% Arg:
0
8
15
0
0
8
43
15
22
8
8
0
0
8
8
% R
% Ser:
29
8
8
22
22
8
8
58
43
15
8
43
29
15
22
% S
% Thr:
8
0
15
8
0
0
0
8
0
8
8
0
8
15
8
% T
% Val:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
0
0
0
8
8
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _