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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WTIP
All Species:
0.91
Human Site:
S291
Identified Species:
1.54
UniProt:
A6NIX2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NIX2
NP_001073905
654
67454
S291
E
A
G
A
D
G
L
S
R
G
E
R
G
P
R
Chimpanzee
Pan troglodytes
XP_001156388
511
54866
R169
S
L
R
P
A
R
G
R
G
E
E
G
A
R
P
Rhesus Macaque
Macaca mulatta
XP_001110152
578
62790
R236
S
L
R
P
P
R
G
R
G
E
E
G
A
R
P
Dog
Lupus familis
XP_541912
655
69604
L271
G
P
E
N
G
A
L
L
G
P
T
Q
P
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQJ8
398
42235
G56
R
R
G
K
G
G
C
G
G
P
E
A
A
P
D
Rat
Rattus norvegicus
Q5U2Z2
548
58063
S206
T
T
A
P
S
G
Y
S
S
G
G
V
P
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513540
700
74650
P326
A
P
G
A
R
G
D
P
L
R
T
N
P
R
G
Chicken
Gallus gallus
Q5F464
604
65121
A253
G
P
G
Q
P
Y
A
A
P
P
A
R
P
P
G
Frog
Xenopus laevis
A9LS46
690
75317
P272
Y
D
Q
R
H
I
S
P
R
S
S
T
A
S
Q
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
G272
D
S
R
F
T
P
A
G
G
H
D
P
E
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572930
728
77943
N355
P
N
Y
I
E
D
I
N
S
S
D
Y
V
C
M
Honey Bee
Apis mellifera
XP_391978
881
97801
P450
Q
E
P
R
A
D
F
P
A
R
N
S
P
I
Y
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
K71
N
I
T
T
S
P
Y
K
R
R
S
S
E
G
K
Sea Urchin
Strong. purpuratus
XP_792799
904
97329
P349
S
E
R
N
H
S
V
P
P
D
I
Y
P
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
46.6
38.3
N.A.
55.9
37.9
N.A.
37.4
28.5
41.2
41.2
N.A.
33
32.1
20.1
29.2
Protein Similarity:
100
65.5
52.7
47
N.A.
57.4
46.7
N.A.
47.8
40.2
51.7
50.7
N.A.
44.3
42.2
31.7
39.4
P-Site Identity:
100
6.6
6.6
6.6
N.A.
26.6
20
N.A.
20
20
6.6
0
N.A.
0
0
6.6
0
P-Site Similarity:
100
6.6
6.6
13.3
N.A.
26.6
20
N.A.
20
26.6
13.3
20
N.A.
26.6
6.6
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
15
15
8
15
8
8
0
8
8
29
0
15
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
8
8
0
0
8
15
8
0
0
8
15
0
0
0
8
% D
% Glu:
8
15
8
0
8
0
0
0
0
15
29
0
15
0
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
29
0
15
29
15
15
36
15
8
15
8
8
15
% G
% His:
0
0
0
0
15
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
0
8
0
8
0
8
8
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% K
% Leu:
0
15
0
0
0
0
15
8
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
8
0
15
0
0
0
8
0
0
8
8
0
0
0
% N
% Pro:
8
22
8
22
15
15
0
29
15
22
0
8
43
22
15
% P
% Gln:
8
0
8
8
0
0
0
0
0
0
0
8
0
0
8
% Q
% Arg:
8
8
29
15
8
15
0
15
22
22
0
15
0
29
8
% R
% Ser:
22
8
0
0
15
8
8
15
15
15
15
15
0
29
0
% S
% Thr:
8
8
8
8
8
0
0
0
0
0
15
8
0
0
8
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
8
15
0
0
0
0
15
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _