Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 1.52
Human Site: S306 Identified Species: 2.56
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S306 R A A V P E L S A Q P A G S P
Chimpanzee Pan troglodytes XP_001156388 511 54866 L184 G A W E L T F L R R A R R R A
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 L251 G V W E R T F L R C A R R R Q
Dog Lupus familis XP_541912 655 69604 A286 P S F L A P L A Q S C P S Q G
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235 G71 V P S R P E R G P R A S L A G
Rat Rattus norvegicus Q5U2Z2 548 58063 L221 Y P E L H A A L D R L C A H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 V341 E K Q T C V V V G E P N G E P
Chicken Gallus gallus Q5F464 604 65121 Q268 A Q Q Y G S P Q P R G P D Y G
Frog Xenopus laevis A9LS46 690 75317 R287 Y S C T T S P R S S Y S D S R
Zebra Danio Brachydanio rerio A8DZE6 648 70883 A287 A V H G I P M A S P R S S I C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 T370 T A N L H R N T A A G L A T G
Honey Bee Apis mellifera XP_391978 881 97801 H465 S S N R S T E H L R L S N L Q
Nematode Worm Caenorhab. elegans Q09476 413 46434 R86 D Y S K S Q E R I Y E N E S R
Sea Urchin Strong. purpuratus XP_792799 904 97329 P364 Q H T N S F L P A P K I R S N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 6.6 0 6.6 N.A. 13.3 0 N.A. 20 0 6.6 0 N.A. 13.3 0 6.6 20
P-Site Similarity: 100 13.3 0 26.6 N.A. 40 13.3 N.A. 33.3 6.6 26.6 26.6 N.A. 33.3 20 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 22 8 0 8 8 8 15 22 8 22 8 15 8 8 % A
% Cys: 0 0 8 0 8 0 0 0 0 8 8 8 0 0 8 % C
% Asp: 8 0 0 0 0 0 0 0 8 0 0 0 15 0 0 % D
% Glu: 8 0 8 15 0 15 15 0 0 8 8 0 8 8 0 % E
% Phe: 0 0 8 0 0 8 15 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 8 8 0 0 8 8 0 15 0 15 0 29 % G
% His: 0 8 8 0 15 0 0 8 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 8 0 8 0 % I
% Lys: 0 8 0 8 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 0 22 8 0 22 22 8 0 15 8 8 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 15 8 0 0 8 0 0 0 0 15 8 0 8 % N
% Pro: 8 15 0 0 15 15 15 8 15 15 15 15 0 0 15 % P
% Gln: 8 8 15 0 0 8 0 8 8 8 0 0 0 8 15 % Q
% Arg: 8 0 0 15 8 8 8 15 15 36 8 15 22 15 22 % R
% Ser: 8 22 15 0 22 15 0 8 15 15 0 29 15 29 0 % S
% Thr: 8 0 8 15 8 22 0 8 0 0 0 0 0 8 0 % T
% Val: 8 15 0 8 0 8 8 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 8 0 8 0 0 0 0 0 8 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _