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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 2.73
Human Site: S320 Identified Species: 4.62
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S320 P R A S L A G S D G G G G G G
Chimpanzee Pan troglodytes XP_001156388 511 54866 R198 A G L G Y D Q R H G S P R S G
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 L265 Q K G V L P R L P R H G M G V
Dog Lupus familis XP_541912 655 69604 S300 G A L P R A N S G M G S E V A
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235 R85 G S D G G S A R S S G I S L G
Rat Rattus norvegicus Q5U2Z2 548 58063 Q235 R P V G F G C Q E S R H S Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 S355 P Q L W L Q G S P A S Y I S S
Chicken Gallus gallus Q5F464 604 65121 R282 G Y A P P P A R P S E P S Y G
Frog Xenopus laevis A9LS46 690 75317 P301 R Y V P S G N P D L D G V G G
Zebra Danio Brachydanio rerio A8DZE6 648 70883 A301 C S Q P A V A A N C V V S P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 A384 G R A A A T G A P A Q R T V Q
Honey Bee Apis mellifera XP_391978 881 97801 Q479 Q N D R N F V Q E V L D P S E
Nematode Worm Caenorhab. elegans Q09476 413 46434 S100 R L N P P V Y S R P S V Q S L
Sea Urchin Strong. purpuratus XP_792799 904 97329 P378 N S H D H P Y P A Q H S T D Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 13.3 20 20 N.A. 13.3 0 N.A. 26.6 13.3 26.6 0 N.A. 20 0 6.6 0
P-Site Similarity: 100 13.3 26.6 20 N.A. 20 6.6 N.A. 33.3 13.3 26.6 13.3 N.A. 33.3 6.6 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 22 8 15 15 22 15 8 15 0 0 0 0 8 % A
% Cys: 8 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 15 8 0 8 0 0 15 0 8 8 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 15 0 8 0 8 0 8 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 29 8 8 22 8 15 22 0 8 15 22 22 8 22 36 % G
% His: 0 0 8 0 8 0 0 0 8 0 15 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 22 0 22 0 0 8 0 8 8 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % M
% Asn: 8 8 8 0 8 0 15 0 8 0 0 0 0 0 0 % N
% Pro: 15 8 0 36 15 22 0 15 29 8 0 15 8 8 8 % P
% Gln: 15 8 8 0 0 8 8 15 0 8 8 0 8 0 8 % Q
% Arg: 22 15 0 8 8 0 8 22 8 8 8 8 8 0 8 % R
% Ser: 0 22 0 8 8 8 0 29 8 22 22 15 29 29 8 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 15 0 0 % T
% Val: 0 0 15 8 0 15 8 0 0 8 8 15 8 15 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 0 8 0 15 0 0 0 0 8 0 15 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _