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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WTIP
All Species:
7.27
Human Site:
S335
Identified Species:
12.31
UniProt:
A6NIX2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NIX2
NP_001073905
654
67454
S335
S
A
R
S
S
G
I
S
L
G
Y
D
Q
R
H
Chimpanzee
Pan troglodytes
XP_001156388
511
54866
P213
R
S
D
P
R
P
G
P
G
P
P
S
V
G
S
Rhesus Macaque
Macaca mulatta
XP_001110152
578
62790
W280
D
S
N
R
E
V
E
W
P
R
Y
H
R
T
P
Dog
Lupus familis
XP_541912
655
69604
V315
G
A
M
P
K
P
T
V
D
P
Q
A
W
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQJ8
398
42235
G100
Y
D
Q
R
H
G
P
G
P
G
P
P
S
G
G
Rat
Rattus norvegicus
Q5U2Z2
548
58063
A250
P
A
L
G
S
P
G
A
L
T
G
A
V
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513540
700
74650
S370
S
V
P
A
P
L
P
S
G
I
D
C
E
P
P
Chicken
Gallus gallus
Q5F464
604
65121
Y297
Y
A
P
Q
Q
G
R
Y
Q
D
P
Y
Y
G
G
Frog
Xenopus laevis
A9LS46
690
75317
R316
H
G
S
L
V
S
P
R
S
S
M
C
L
Q
E
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
S316
S
S
I
S
S
H
S
S
R
S
S
R
S
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572930
728
77943
S399
E
P
P
I
I
T
S
S
L
A
M
G
M
A
T
Honey Bee
Apis mellifera
XP_391978
881
97801
Y494
T
S
K
P
S
P
M
Y
S
P
S
R
N
D
N
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
P115
L
S
Q
V
E
E
P
P
I
R
A
S
S
S
R
Sea Urchin
Strong. purpuratus
XP_792799
904
97329
S393
Q
D
L
W
S
A
Q
S
Q
G
E
T
E
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
46.6
38.3
N.A.
55.9
37.9
N.A.
37.4
28.5
41.2
41.2
N.A.
33
32.1
20.1
29.2
Protein Similarity:
100
65.5
52.7
47
N.A.
57.4
46.7
N.A.
47.8
40.2
51.7
50.7
N.A.
44.3
42.2
31.7
39.4
P-Site Identity:
100
0
6.6
6.6
N.A.
13.3
20
N.A.
13.3
13.3
0
26.6
N.A.
13.3
6.6
0
20
P-Site Similarity:
100
6.6
20
6.6
N.A.
20
26.6
N.A.
26.6
13.3
6.6
33.3
N.A.
13.3
40
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
0
8
0
8
0
8
0
8
8
15
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% C
% Asp:
8
15
8
0
0
0
0
0
8
8
8
8
0
8
0
% D
% Glu:
8
0
0
0
15
8
8
0
0
0
8
0
15
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
8
0
8
0
22
15
8
15
22
8
8
0
22
29
% G
% His:
8
0
0
0
8
8
0
0
0
0
0
8
0
0
8
% H
% Ile:
0
0
8
8
8
0
8
0
8
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
15
8
0
8
0
0
22
0
0
0
8
0
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
15
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
8
8
22
22
8
29
29
15
15
22
22
8
0
8
22
% P
% Gln:
8
0
15
8
8
0
8
0
15
0
8
0
8
15
0
% Q
% Arg:
8
0
8
15
8
0
8
8
8
15
0
15
8
8
15
% R
% Ser:
22
36
8
15
36
8
15
36
15
15
15
15
22
15
8
% S
% Thr:
8
0
0
0
0
8
8
0
0
8
0
8
0
8
8
% T
% Val:
0
8
0
8
8
8
0
8
0
0
0
0
15
8
0
% V
% Trp:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% W
% Tyr:
15
0
0
0
0
0
0
15
0
0
15
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _