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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 6.67
Human Site: S347 Identified Species: 11.28
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S347 Q R H G S P R S G R S D P R P
Chimpanzee Pan troglodytes XP_001156388 511 54866 V225 V G S A R S S V S S L G S R G
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 F292 R T P P D P G F G D G S G G R
Dog Lupus familis XP_541912 655 69604 S327 W F P D G P K S Y L S S S V P
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235 S112 S G G S A R S S V S S L G S R
Rat Rattus norvegicus Q5U2Z2 548 58063 L262 V V G T A G P L E R R G T Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 L382 E P P G A A C L K P F G P L G
Chicken Gallus gallus Q5F464 604 65121 N309 Y G G Y G G R N G S E A P Y M
Frog Xenopus laevis A9LS46 690 75317 T328 L Q E G R S A T L G S C N P S
Zebra Danio Brachydanio rerio A8DZE6 648 70883 A328 S S R G S M S A Y P E L Q L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 T411 M A T A A P P T T S N A P T S
Honey Bee Apis mellifera XP_391978 881 97801 T506 N D N S R I I T N N N N I R G
Nematode Worm Caenorhab. elegans Q09476 413 46434 P127 S S R K S L G P P S Q A Q S Y
Sea Urchin Strong. purpuratus XP_792799 904 97329 A405 E Q G D M S Q A R R P Q S S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 6.6 13.3 26.6 N.A. 13.3 13.3 N.A. 13.3 20 13.3 20 N.A. 13.3 6.6 6.6 6.6
P-Site Similarity: 100 6.6 20 33.3 N.A. 20 26.6 N.A. 26.6 26.6 26.6 26.6 N.A. 33.3 33.3 6.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 15 29 8 8 15 0 0 0 22 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % C
% Asp: 0 8 0 15 8 0 0 0 0 8 0 8 0 0 0 % D
% Glu: 15 0 8 0 0 0 0 0 8 0 15 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 8 0 0 8 0 0 0 0 % F
% Gly: 0 22 29 29 15 15 15 0 22 8 8 22 15 8 22 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 8 0 0 8 0 8 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 8 0 15 8 8 8 15 0 15 0 % L
% Met: 8 0 0 0 8 8 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 0 8 0 0 0 0 8 8 8 15 8 8 0 0 % N
% Pro: 0 8 22 8 0 29 15 8 8 15 8 0 29 8 29 % P
% Gln: 8 15 0 0 0 0 8 0 0 0 8 8 15 8 0 % Q
% Arg: 8 8 15 0 22 8 15 0 8 22 8 0 0 22 15 % R
% Ser: 22 15 8 15 22 22 22 22 8 36 29 15 22 22 22 % S
% Thr: 0 8 8 8 0 0 0 22 8 0 0 0 8 8 0 % T
% Val: 15 8 0 0 0 0 0 8 8 0 0 0 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 0 0 0 0 15 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _