Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 8.48
Human Site: S367 Identified Species: 14.36
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S367 S V G S A R S S V S S L G S R
Chimpanzee Pan troglodytes XP_001156388 511 54866 A245 A D F L P P G A C P A P A R S
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 G312 G R K A H F G G E G N H A S H
Dog Lupus familis XP_541912 655 69604 G347 S M D S L Q S G A A P G L G P
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235 G132 C A D L L P P G V G P A P A R
Rat Rattus norvegicus Q5U2Z2 548 58063 A282 T G Y G D C A A G A R Y Q D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 P402 H G P S C L N P S P N P G S F
Chicken Gallus gallus Q5F464 604 65121 S329 K V E P A Y P S S N T V G Q A
Frog Xenopus laevis A9LS46 690 75317 S348 S S I S S H S S R S S R S S R
Zebra Danio Brachydanio rerio A8DZE6 648 70883 Q348 L P E D A L L Q D F T E P N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 S431 A A P T S T A S L R A T P I A
Honey Bee Apis mellifera XP_391978 881 97801 S526 P T H N Q I S S D T V A Q N V
Nematode Worm Caenorhab. elegans Q09476 413 46434 D147 N G R S P S R D P L H S D S M
Sea Urchin Strong. purpuratus XP_792799 904 97329 M425 K I S S E R N M P L P E G N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 0 6.6 20 N.A. 13.3 0 N.A. 20 26.6 53.3 6.6 N.A. 6.6 13.3 13.3 20
P-Site Similarity: 100 20 20 40 N.A. 20 26.6 N.A. 33.3 46.6 60 20 N.A. 46.6 33.3 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 0 8 22 0 15 15 8 15 15 15 15 8 15 % A
% Cys: 8 0 0 0 8 8 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 8 15 8 8 0 0 8 15 0 0 0 8 8 0 % D
% Glu: 0 0 15 0 8 0 0 0 8 0 0 15 0 0 8 % E
% Phe: 0 0 8 0 0 8 0 0 0 8 0 0 0 0 8 % F
% Gly: 8 22 8 8 0 0 15 22 8 15 0 8 29 8 8 % G
% His: 8 0 8 0 8 8 0 0 0 0 8 8 0 0 8 % H
% Ile: 0 8 8 0 0 8 0 0 0 0 0 0 0 8 0 % I
% Lys: 15 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 15 15 15 8 0 8 15 0 8 8 0 0 % L
% Met: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 8 % M
% Asn: 8 0 0 8 0 0 15 0 0 8 15 0 0 22 0 % N
% Pro: 8 8 15 8 15 15 15 8 15 15 22 15 22 0 8 % P
% Gln: 0 0 0 0 8 8 0 8 0 0 0 0 15 8 0 % Q
% Arg: 0 8 8 0 0 15 8 0 8 8 8 8 0 8 22 % R
% Ser: 22 8 8 43 15 8 29 36 15 15 15 8 8 36 15 % S
% Thr: 8 8 0 8 0 8 0 0 0 8 15 8 0 0 0 % T
% Val: 0 15 0 0 0 0 0 0 15 0 8 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _