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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 4.85
Human Site: S369 Identified Species: 8.21
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S369 G S A R S S V S S L G S R G S
Chimpanzee Pan troglodytes XP_001156388 511 54866 P247 F L P P G A C P A P A R S P E
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 G314 K A H F G G E G N H A S H T W
Dog Lupus familis XP_541912 655 69604 A349 D S L Q S G A A P G L G P K P
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235 G134 D L L P P G V G P A P A R S P
Rat Rattus norvegicus Q5U2Z2 548 58063 A284 Y G D C A A G A R Y Q D E L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 P404 P S C L N P S P N P G S F P S
Chicken Gallus gallus Q5F464 604 65121 N331 E P A Y P S S N T V G Q A P P
Frog Xenopus laevis A9LS46 690 75317 S350 I S S H S S R S S R S S R G S
Zebra Danio Brachydanio rerio A8DZE6 648 70883 F350 E D A L L Q D F T E P N G L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 R433 P T S T A S L R A T P I A M T
Honey Bee Apis mellifera XP_391978 881 97801 T528 H N Q I S S D T V A Q N V I N
Nematode Worm Caenorhab. elegans Q09476 413 46434 L149 R S P S R D P L H S D S M I G
Sea Urchin Strong. purpuratus XP_792799 904 97329 L427 S S E R N M P L P E G N S G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 0 6.6 13.3 N.A. 13.3 0 N.A. 26.6 20 60 6.6 N.A. 6.6 13.3 13.3 26.6
P-Site Similarity: 100 13.3 20 26.6 N.A. 20 26.6 N.A. 40 40 66.6 20 N.A. 46.6 40 13.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 22 0 15 15 8 15 15 15 15 8 15 0 8 % A
% Cys: 0 0 8 8 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 15 8 8 0 0 8 15 0 0 0 8 8 0 0 0 % D
% Glu: 15 0 8 0 0 0 8 0 0 15 0 0 8 0 8 % E
% Phe: 8 0 0 8 0 0 0 8 0 0 0 0 8 0 0 % F
% Gly: 8 8 0 0 15 22 8 15 0 8 29 8 8 22 8 % G
% His: 8 0 8 8 0 0 0 0 8 8 0 0 8 0 8 % H
% Ile: 8 0 0 8 0 0 0 0 0 0 0 8 0 15 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 0 15 15 15 8 0 8 15 0 8 8 0 0 15 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 0 % M
% Asn: 0 8 0 0 15 0 0 8 15 0 0 22 0 0 8 % N
% Pro: 15 8 15 15 15 8 15 15 22 15 22 0 8 22 22 % P
% Gln: 0 0 8 8 0 8 0 0 0 0 15 8 0 0 0 % Q
% Arg: 8 0 0 15 8 0 8 8 8 8 0 8 22 0 0 % R
% Ser: 8 43 15 8 29 36 15 15 15 8 8 36 15 8 22 % S
% Thr: 0 8 0 8 0 0 0 8 15 8 0 0 0 8 15 % T
% Val: 0 0 0 0 0 0 15 0 8 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 8 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _