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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WTIP
All Species:
5.76
Human Site:
S370
Identified Species:
9.74
UniProt:
A6NIX2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NIX2
NP_001073905
654
67454
S370
S
A
R
S
S
V
S
S
L
G
S
R
G
S
A
Chimpanzee
Pan troglodytes
XP_001156388
511
54866
A248
L
P
P
G
A
C
P
A
P
A
R
S
P
E
P
Rhesus Macaque
Macaca mulatta
XP_001110152
578
62790
N315
A
H
F
G
G
E
G
N
H
A
S
H
T
W
L
Dog
Lupus familis
XP_541912
655
69604
P350
S
L
Q
S
G
A
A
P
G
L
G
P
K
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQJ8
398
42235
P135
L
L
P
P
G
V
G
P
A
P
A
R
S
P
E
Rat
Rattus norvegicus
Q5U2Z2
548
58063
R285
G
D
C
A
A
G
A
R
Y
Q
D
E
L
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513540
700
74650
N405
S
C
L
N
P
S
P
N
P
G
S
F
P
S
P
Chicken
Gallus gallus
Q5F464
604
65121
T332
P
A
Y
P
S
S
N
T
V
G
Q
A
P
P
G
Frog
Xenopus laevis
A9LS46
690
75317
S351
S
S
H
S
S
R
S
S
R
S
S
R
G
S
M
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
T351
D
A
L
L
Q
D
F
T
E
P
N
G
L
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572930
728
77943
A434
T
S
T
A
S
L
R
A
T
P
I
A
M
T
A
Honey Bee
Apis mellifera
XP_391978
881
97801
V529
N
Q
I
S
S
D
T
V
A
Q
N
V
I
N
S
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
H150
S
P
S
R
D
P
L
H
S
D
S
M
I
G
T
Sea Urchin
Strong. purpuratus
XP_792799
904
97329
P428
S
E
R
N
M
P
L
P
E
G
N
S
G
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
46.6
38.3
N.A.
55.9
37.9
N.A.
37.4
28.5
41.2
41.2
N.A.
33
32.1
20.1
29.2
Protein Similarity:
100
65.5
52.7
47
N.A.
57.4
46.7
N.A.
47.8
40.2
51.7
50.7
N.A.
44.3
42.2
31.7
39.4
P-Site Identity:
100
0
6.6
13.3
N.A.
13.3
6.6
N.A.
26.6
20
60
6.6
N.A.
13.3
13.3
13.3
26.6
P-Site Similarity:
100
13.3
20
26.6
N.A.
20
33.3
N.A.
40
40
66.6
20
N.A.
53.3
46.6
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
0
15
15
8
15
15
15
15
8
15
0
8
22
% A
% Cys:
0
8
8
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
15
0
0
0
8
8
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
15
0
0
8
0
8
8
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
15
22
8
15
0
8
29
8
8
22
8
8
% G
% His:
0
8
8
0
0
0
0
8
8
0
0
8
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
8
0
15
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
15
15
15
8
0
8
15
0
8
8
0
0
15
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
8
% M
% Asn:
8
0
0
15
0
0
8
15
0
0
22
0
0
8
8
% N
% Pro:
8
15
15
15
8
15
15
22
15
22
0
8
22
22
15
% P
% Gln:
0
8
8
0
8
0
0
0
0
15
8
0
0
0
0
% Q
% Arg:
0
0
15
8
0
8
8
8
8
0
8
22
0
0
8
% R
% Ser:
43
15
8
29
36
15
15
15
8
8
36
15
8
22
8
% S
% Thr:
8
0
8
0
0
0
8
15
8
0
0
0
8
15
8
% T
% Val:
0
0
0
0
0
15
0
8
8
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _