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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 29.39
Human Site: S595 Identified Species: 49.74
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S595 E T T I R V V S M D R D Y H V
Chimpanzee Pan troglodytes XP_001156388 511 54866 C461 D R D Y H V A C Y H C E D C G
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 C528 D R D Y H V A C Y H C E D C G
Dog Lupus familis XP_541912 655 69604 S597 D E T I R V V S M D R D Y H V
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235 C348 D R D Y H V E C Y H C E D C G
Rat Rattus norvegicus Q5U2Z2 548 58063 D498 R V I S M D R D Y H F E C Y H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 S642 D E T I R V V S M D R D Y H V
Chicken Gallus gallus Q5F464 604 65121 A549 E E T V R I V A L D R D F H V
Frog Xenopus laevis A9LS46 690 75317 S627 E E T I R V V S M D K D Y H V
Zebra Danio Brachydanio rerio A8DZE6 648 70883 S585 E E T I R V V S M D K D Y H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 S662 D E T V R V V S M D K D F H V
Honey Bee Apis mellifera XP_391978 881 97801 S818 E E T V R V V S M D K D F H V
Nematode Worm Caenorhab. elegans Q09476 413 46434 R363 C R G A I N G R C V A A M G R
Sea Urchin Strong. purpuratus XP_792799 904 97329 S688 M E T V R V V S M D K D F H V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 6.6 6.6 86.6 N.A. 6.6 0 N.A. 86.6 60 86.6 86.6 N.A. 66.6 73.3 0 66.6
P-Site Similarity: 100 20 20 93.3 N.A. 20 13.3 N.A. 93.3 93.3 93.3 93.3 N.A. 93.3 93.3 0 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 15 8 0 0 8 8 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 22 8 0 22 0 8 22 0 % C
% Asp: 43 0 22 0 0 8 0 8 0 65 0 65 22 0 0 % D
% Glu: 36 58 0 0 0 0 8 0 0 0 0 29 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 29 0 0 % F
% Gly: 0 0 8 0 0 0 8 0 0 0 0 0 0 8 22 % G
% His: 0 0 0 0 22 0 0 0 0 29 0 0 0 65 8 % H
% Ile: 0 0 8 36 8 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % L
% Met: 8 0 0 0 8 0 0 0 58 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 29 0 0 65 0 8 8 0 0 29 0 0 0 8 % R
% Ser: 0 0 0 8 0 0 0 58 0 0 0 0 0 0 0 % S
% Thr: 0 8 65 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 29 0 79 65 0 0 8 0 0 0 0 65 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 22 0 0 0 0 29 0 0 0 36 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _