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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 2.12
Human Site: S75 Identified Species: 3.59
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 S75 V G P A A P E S K A A Q G R E
Chimpanzee Pan troglodytes XP_001156388 511 54866
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 S56 R C W K R E E S P H F T G T A
Dog Lupus familis XP_541912 655 69604 Q62 I H L Q Q Q Q Q Q L L Q E E T
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235
Rat Rattus norvegicus Q5U2Z2 548 58063 G26 D S G S A K F G R R K G E A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 V80 G G P L N G G V R L G P Q A H
Chicken Gallus gallus Q5F464 604 65121 N56 V A P K P K Y N P Y K Q P G G
Frog Xenopus laevis A9LS46 690 75317 K67 L P H S S S D K V Y P L G S S
Zebra Danio Brachydanio rerio A8DZE6 648 70883 Q78 P L D F C S P Q R E A V Y P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 Q74 L Q E S Q Q Q Q Q Q H Q M Q Q
Honey Bee Apis mellifera XP_391978 881 97801 S67 R P V G A I E S F I E S N T D
Nematode Worm Caenorhab. elegans Q09476 413 46434
Sea Urchin Strong. purpuratus XP_792799 904 97329 N150 V T E S H T K N R G L R P N E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 0 20 6.6 N.A. 0 6.6 N.A. 13.3 20 6.6 6.6 N.A. 6.6 20 0 13.3
P-Site Similarity: 100 0 20 26.6 N.A. 0 20 N.A. 20 26.6 33.3 20 N.A. 46.6 26.6 0 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 22 0 0 0 0 8 15 0 0 15 8 % A
% Cys: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 0 8 0 0 0 0 0 0 0 15 % D
% Glu: 0 0 15 0 0 8 22 0 0 8 8 0 15 8 15 % E
% Phe: 0 0 0 8 0 0 8 0 8 0 8 0 0 0 0 % F
% Gly: 8 15 8 8 0 8 8 8 0 8 8 8 22 8 8 % G
% His: 0 8 8 0 8 0 0 0 0 8 8 0 0 0 8 % H
% Ile: 8 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 15 0 15 8 8 8 0 15 0 0 0 0 % K
% Leu: 15 8 8 8 0 0 0 0 0 15 15 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 8 0 0 15 0 0 0 0 8 8 0 % N
% Pro: 8 15 22 0 8 8 8 0 15 0 8 8 15 8 0 % P
% Gln: 0 8 0 8 15 15 15 22 15 8 0 29 8 8 8 % Q
% Arg: 15 0 0 0 8 0 0 0 29 8 0 8 0 8 0 % R
% Ser: 0 8 0 29 8 15 0 22 0 0 0 8 0 8 15 % S
% Thr: 0 8 0 0 0 8 0 0 0 0 0 8 0 15 8 % T
% Val: 22 0 8 0 0 0 0 8 8 0 0 8 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 15 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _