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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WTIP
All Species:
23.94
Human Site:
T430
Identified Species:
40.51
UniProt:
A6NIX2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NIX2
NP_001073905
654
67454
T430
E
R
R
L
E
A
L
T
R
E
L
E
R
A
L
Chimpanzee
Pan troglodytes
XP_001156388
511
54866
T298
E
R
A
L
E
A
R
T
A
R
D
Y
F
G
I
Rhesus Macaque
Macaca mulatta
XP_001110152
578
62790
V365
W
V
V
A
T
L
M
V
P
M
S
V
I
S
I
Dog
Lupus familis
XP_541912
655
69604
T432
E
L
K
L
E
A
L
T
Q
R
L
E
R
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQJ8
398
42235
T185
E
R
A
L
E
A
R
T
A
R
D
Y
F
G
I
Rat
Rattus norvegicus
Q5U2Z2
548
58063
I335
P
E
A
S
R
S
R
I
R
E
P
E
A
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513540
700
74650
T477
E
L
K
L
E
A
L
T
Q
R
L
E
Q
E
M
Chicken
Gallus gallus
Q5F464
604
65121
E384
P
A
F
R
P
E
D
E
L
E
H
L
T
K
K
Frog
Xenopus laevis
A9LS46
690
75317
T462
E
R
R
L
E
A
L
T
L
E
L
E
K
E
L
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
T420
E
R
R
L
E
A
L
T
L
E
L
E
K
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572930
728
77943
R497
R
K
I
E
E
L
T
R
Q
L
E
E
E
I
E
Honey Bee
Apis mellifera
XP_391978
881
97801
R653
R
K
I
E
E
L
T
R
Q
L
E
E
E
M
E
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
Y200
K
M
W
H
P
E
H
Y
T
C
C
E
C
G
A
Sea Urchin
Strong. purpuratus
XP_792799
904
97329
T510
E
R
K
L
E
E
L
T
Q
Q
L
E
K
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
46.6
38.3
N.A.
55.9
37.9
N.A.
37.4
28.5
41.2
41.2
N.A.
33
32.1
20.1
29.2
Protein Similarity:
100
65.5
52.7
47
N.A.
57.4
46.7
N.A.
47.8
40.2
51.7
50.7
N.A.
44.3
42.2
31.7
39.4
P-Site Identity:
100
40
0
60
N.A.
40
20
N.A.
53.3
6.6
80
80
N.A.
13.3
13.3
6.6
60
P-Site Similarity:
100
46.6
20
80
N.A.
46.6
26.6
N.A.
80
6.6
86.6
86.6
N.A.
26.6
26.6
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
22
8
0
50
0
0
15
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
15
0
0
0
0
% D
% Glu:
58
8
0
15
72
22
0
8
0
36
15
72
15
36
22
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
22
0
% G
% His:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
8
0
0
0
0
8
8
22
% I
% Lys:
8
15
22
0
0
0
0
0
0
0
0
0
22
8
8
% K
% Leu:
0
15
0
58
0
22
43
0
22
15
43
8
0
0
29
% L
% Met:
0
8
0
0
0
0
8
0
0
8
0
0
0
8
15
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
0
15
0
0
0
8
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
36
8
0
0
8
0
0
% Q
% Arg:
15
43
22
8
8
0
22
15
15
29
0
0
15
8
0
% R
% Ser:
0
0
0
8
0
8
0
0
0
0
8
0
0
8
0
% S
% Thr:
0
0
0
0
8
0
15
58
8
0
0
0
8
0
0
% T
% Val:
0
8
8
0
0
0
0
8
0
0
0
8
0
0
0
% V
% Trp:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _