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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WTIP
All Species:
3.94
Human Site:
Y380
Identified Species:
6.67
UniProt:
A6NIX2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NIX2
NP_001073905
654
67454
Y380
S
R
G
S
A
G
A
Y
A
D
F
L
P
P
G
Chimpanzee
Pan troglodytes
XP_001156388
511
54866
P258
R
S
P
E
P
A
G
P
A
P
F
P
L
P
A
Rhesus Macaque
Macaca mulatta
XP_001110152
578
62790
P325
S
H
T
W
L
P
S
P
G
L
C
C
G
H
R
Dog
Lupus familis
XP_541912
655
69604
D360
G
P
K
P
V
C
T
D
P
G
M
G
P
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQJ8
398
42235
Q145
A
R
S
P
E
P
A
Q
F
P
F
P
L
P
S
Rat
Rattus norvegicus
Q5U2Z2
548
58063
R295
D
E
L
T
A
L
L
R
L
T
V
A
T
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513540
700
74650
T415
S
F
P
S
P
R
P
T
V
S
D
A
P
P
S
Chicken
Gallus gallus
Q5F464
604
65121
Q342
Q
A
P
P
G
M
Y
Q
H
P
G
P
K
K
T
Frog
Xenopus laevis
A9LS46
690
75317
Y361
S
R
G
S
M
G
A
Y
T
D
L
T
V
P
S
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
V361
N
G
L
H
N
N
R
V
H
L
Q
T
F
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572930
728
77943
A444
I
A
M
T
A
P
L
A
V
A
T
S
P
T
P
Honey Bee
Apis mellifera
XP_391978
881
97801
H539
N
V
I
N
S
P
R
H
V
S
P
S
S
T
N
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
G160
S
M
I
G
T
M
N
G
E
L
S
S
K
H
G
Sea Urchin
Strong. purpuratus
XP_792799
904
97329
D438
N
S
G
A
R
V
A
D
R
A
A
M
Y
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
46.6
38.3
N.A.
55.9
37.9
N.A.
37.4
28.5
41.2
41.2
N.A.
33
32.1
20.1
29.2
Protein Similarity:
100
65.5
52.7
47
N.A.
57.4
46.7
N.A.
47.8
40.2
51.7
50.7
N.A.
44.3
42.2
31.7
39.4
P-Site Identity:
100
20
6.6
6.6
N.A.
26.6
13.3
N.A.
26.6
0
60
6.6
N.A.
13.3
0
13.3
13.3
P-Site Similarity:
100
20
13.3
6.6
N.A.
33.3
20
N.A.
26.6
0
60
13.3
N.A.
20
26.6
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
8
22
8
29
8
15
15
8
15
0
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
15
0
15
8
0
0
0
0
% D
% Glu:
0
8
0
8
8
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
8
0
22
0
8
0
0
% F
% Gly:
8
8
22
8
8
15
8
8
8
8
8
8
8
8
22
% G
% His:
0
8
0
8
0
0
0
8
15
0
0
0
0
15
0
% H
% Ile:
8
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
15
15
0
% K
% Leu:
0
0
15
0
8
8
15
0
8
22
8
8
15
0
8
% L
% Met:
0
8
8
0
8
15
0
0
0
0
8
8
0
0
0
% M
% Asn:
22
0
0
8
8
8
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
22
22
15
29
8
15
8
22
8
22
29
43
8
% P
% Gln:
8
0
0
0
0
0
0
15
0
0
8
0
0
0
0
% Q
% Arg:
8
22
0
0
8
8
15
8
8
0
0
0
0
0
8
% R
% Ser:
36
15
8
22
8
0
8
0
0
15
8
22
8
0
22
% S
% Thr:
0
0
8
15
8
0
8
8
8
8
8
15
8
22
15
% T
% Val:
0
8
0
0
8
8
0
8
22
0
8
0
8
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
15
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _