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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WTIP
All Species:
23.03
Human Site:
Y490
Identified Species:
38.97
UniProt:
A6NIX2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NIX2
NP_001073905
654
67454
Y490
R
L
R
G
K
A
F
Y
N
V
G
E
K
V
Y
Chimpanzee
Pan troglodytes
XP_001156388
511
54866
D358
E
K
V
Y
C
Q
E
D
F
L
Y
S
G
F
Q
Rhesus Macaque
Macaca mulatta
XP_001110152
578
62790
D425
E
K
V
Y
C
Q
E
D
F
L
Y
S
G
F
Q
Dog
Lupus familis
XP_541912
655
69604
Y492
K
L
R
G
K
A
F
Y
F
V
N
G
K
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQJ8
398
42235
D245
E
K
V
Y
C
Q
E
D
F
L
Y
S
G
F
Q
Rat
Rattus norvegicus
Q5U2Z2
548
58063
V395
F
Y
S
V
N
G
S
V
Y
C
E
E
D
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513540
700
74650
Y537
K
L
R
G
K
A
F
Y
F
V
N
G
K
V
F
Chicken
Gallus gallus
Q5F464
604
65121
R444
M
M
C
N
N
K
L
R
G
Q
P
F
Y
A
V
Frog
Xenopus laevis
A9LS46
690
75317
Y522
R
L
R
G
K
A
F
Y
N
V
N
G
K
V
Y
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
Y480
R
L
R
G
K
A
F
Y
N
V
N
G
K
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572930
728
77943
Y557
A
L
R
G
K
A
F
Y
N
V
H
G
R
V
Y
Honey Bee
Apis mellifera
XP_391978
881
97801
Y713
A
L
R
G
K
A
F
Y
N
V
H
G
R
V
Y
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
T260
N
F
H
I
E
C
F
T
C
A
E
C
N
Q
P
Sea Urchin
Strong. purpuratus
XP_792799
904
97329
G570
P
Y
A
G
V
S
W
G
K
S
L
S
R
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
46.6
38.3
N.A.
55.9
37.9
N.A.
37.4
28.5
41.2
41.2
N.A.
33
32.1
20.1
29.2
Protein Similarity:
100
65.5
52.7
47
N.A.
57.4
46.7
N.A.
47.8
40.2
51.7
50.7
N.A.
44.3
42.2
31.7
39.4
P-Site Identity:
100
0
0
66.6
N.A.
0
6.6
N.A.
66.6
0
86.6
86.6
N.A.
73.3
73.3
6.6
6.6
P-Site Similarity:
100
6.6
6.6
80
N.A.
6.6
6.6
N.A.
80
6.6
86.6
86.6
N.A.
80
80
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
0
0
50
0
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
8
0
22
8
0
0
8
8
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
22
0
0
0
0
8
0
0
% D
% Glu:
22
0
0
0
8
0
22
0
0
0
15
15
0
0
0
% E
% Phe:
8
8
0
0
0
0
58
0
36
0
0
8
0
22
15
% F
% Gly:
0
0
0
58
0
8
0
8
8
0
8
43
22
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
15
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
15
22
0
0
50
8
0
0
8
0
0
0
36
0
0
% K
% Leu:
0
50
0
0
0
0
8
0
0
22
8
0
0
0
15
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
15
0
0
0
36
0
29
0
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
22
0
0
0
8
0
0
0
8
22
% Q
% Arg:
22
0
50
0
0
0
0
8
0
0
0
0
22
0
0
% R
% Ser:
0
0
8
0
0
8
8
0
0
8
0
29
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% T
% Val:
0
0
22
8
8
0
0
8
0
50
0
0
0
50
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
22
0
0
0
50
8
0
22
0
8
8
36
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _