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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WTIP All Species: 28.48
Human Site: Y566 Identified Species: 48.21
UniProt: A6NIX2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NIX2 NP_001073905 654 67454 Y566 N I Y C V R D Y H T V F A P K
Chimpanzee Pan troglodytes XP_001156388 511 54866 A432 T V F A P K C A S C A R P I L
Rhesus Macaque Macaca mulatta XP_001110152 578 62790 A499 T V F A P K C A S C A R P I L
Dog Lupus familis XP_541912 655 69604 Y568 K I Y C V R D Y H K V L A P K
Cat Felis silvestris
Mouse Mus musculus Q7TQJ8 398 42235 A319 T V F A P K C A S C A R P I L
Rat Rattus norvegicus Q5U2Z2 548 58063 Y469 V T D Y H K N Y A P K C A A C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 Y613 K I Y C V K D Y H K V L A P K
Chicken Gallus gallus Q5F464 604 65121 F520 N I H C I E D F H K K F A P R
Frog Xenopus laevis A9LS46 690 75317 Y598 N I Y C V K D Y H T V F A P K
Zebra Danio Brachydanio rerio A8DZE6 648 70883 Y556 N I Y C V K D Y H T V F A P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 Y633 K I Y C V N D Y H R M F A P K
Honey Bee Apis mellifera XP_391978 881 97801 Y789 K I Y C V N D Y H R M F A P K
Nematode Worm Caenorhab. elegans Q09476 413 46434 E334 F N G A S F F E H N G A P L C
Sea Urchin Strong. purpuratus XP_792799 904 97329 Y659 K I Y C V K D Y H K T Y A P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 46.6 38.3 N.A. 55.9 37.9 N.A. 37.4 28.5 41.2 41.2 N.A. 33 32.1 20.1 29.2
Protein Similarity: 100 65.5 52.7 47 N.A. 57.4 46.7 N.A. 47.8 40.2 51.7 50.7 N.A. 44.3 42.2 31.7 39.4
P-Site Identity: 100 0 0 80 N.A. 0 13.3 N.A. 73.3 53.3 93.3 93.3 N.A. 73.3 73.3 6.6 66.6
P-Site Similarity: 100 20 20 80 N.A. 20 26.6 N.A. 80 80 100 100 N.A. 80 80 6.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 29 0 0 0 22 8 0 22 8 72 8 0 % A
% Cys: 0 0 0 65 0 0 22 0 0 22 0 8 0 0 15 % C
% Asp: 0 0 8 0 0 0 65 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % E
% Phe: 8 0 22 0 0 8 8 8 0 0 0 43 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 8 0 8 0 0 0 72 0 0 0 0 0 0 % H
% Ile: 0 65 0 0 8 0 0 0 0 0 0 0 0 22 0 % I
% Lys: 36 0 0 0 0 58 0 0 0 29 15 0 0 0 58 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 15 0 8 22 % L
% Met: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % M
% Asn: 29 8 0 0 0 15 8 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 22 0 0 0 0 8 0 0 29 65 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 15 0 0 0 15 0 22 0 0 8 % R
% Ser: 0 0 0 0 8 0 0 0 22 0 0 0 0 0 0 % S
% Thr: 22 8 0 0 0 0 0 0 0 22 8 0 0 0 0 % T
% Val: 8 22 0 0 58 0 0 0 0 0 36 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 58 8 0 0 0 65 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _