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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WTIP
All Species:
26.06
Human Site:
Y623
Identified Species:
44.1
UniProt:
A6NIX2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NIX2
NP_001073905
654
67454
Y623
G
E
E
G
R
R
C
Y
P
L
A
G
H
L
L
Chimpanzee
Pan troglodytes
XP_001156388
511
54866
R489
L
A
G
H
L
L
C
R
R
C
H
L
R
R
L
Rhesus Macaque
Macaca mulatta
XP_001110152
578
62790
R556
L
A
G
H
L
L
C
R
R
C
H
L
R
R
L
Dog
Lupus familis
XP_541912
655
69604
Y625
D
E
D
G
H
R
C
Y
P
L
E
D
H
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQJ8
398
42235
R376
L
E
G
H
L
L
C
R
R
C
H
L
R
R
L
Rat
Rattus norvegicus
Q5U2Z2
548
58063
G526
C
C
C
F
P
L
D
G
H
L
L
C
H
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513540
700
74650
Y670
D
E
D
G
H
R
C
Y
P
L
E
D
H
L
L
Chicken
Gallus gallus
Q5F464
604
65121
Y577
E
G
D
N
Q
G
C
Y
P
L
D
G
H
I
L
Frog
Xenopus laevis
A9LS46
690
75317
Y655
D
E
E
G
R
R
C
Y
P
L
E
G
H
L
L
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
Y613
D
E
E
G
H
R
C
Y
P
L
E
G
H
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572930
728
77943
Y690
D
E
P
D
K
R
C
Y
P
L
D
G
R
L
L
Honey Bee
Apis mellifera
XP_391978
881
97801
Y846
D
E
P
D
K
R
C
Y
P
L
D
G
R
L
M
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
F391
H
Q
L
T
K
G
T
F
K
E
V
D
R
R
P
Sea Urchin
Strong. purpuratus
XP_792799
904
97329
Y716
D
D
D
G
H
R
C
Y
P
L
T
D
K
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
46.6
38.3
N.A.
55.9
37.9
N.A.
37.4
28.5
41.2
41.2
N.A.
33
32.1
20.1
29.2
Protein Similarity:
100
65.5
52.7
47
N.A.
57.4
46.7
N.A.
47.8
40.2
51.7
50.7
N.A.
44.3
42.2
31.7
39.4
P-Site Identity:
100
13.3
13.3
60
N.A.
20
13.3
N.A.
66.6
46.6
86.6
80
N.A.
60
53.3
0
53.3
P-Site Similarity:
100
13.3
13.3
66.6
N.A.
20
13.3
N.A.
73.3
66.6
86.6
80
N.A.
66.6
66.6
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
8
8
8
0
0
0
86
0
0
22
0
8
0
0
8
% C
% Asp:
50
8
29
15
0
0
8
0
0
0
22
29
0
0
0
% D
% Glu:
8
58
22
0
0
0
0
0
0
8
29
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
8
8
22
43
0
15
0
8
0
0
0
43
0
8
0
% G
% His:
8
0
0
22
29
0
0
0
8
0
22
0
50
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
22
0
0
0
8
0
0
0
8
0
0
% K
% Leu:
22
0
8
0
22
29
0
0
0
72
8
22
0
58
72
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
15
0
8
0
0
0
65
0
0
0
0
0
8
% P
% Gln:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
15
58
0
22
22
0
0
0
43
29
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _